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Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.19.529123Source: DataRank Database

Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 5 times.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (29)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (24)

Luca Paruzzo ORCID,Katharina E. Hayer ORCID,Carolin Schmidt,Manuel Torres-Diz ORCID,Feng Xu ORCID

Live enrichment

PubMed:37645778 OpenAlex:https://openalex.org/W4321377491

National Institutes of Health

Grant: 5T32CA009615-24

Cancer Center Research Training Program

National Institutes of Health

Grant: 3U01CA232563-01S2

Cassette exons in neoplastic pro-B-cells: implications for immunotherapy

National Institutes of Health

Grant: 5U01CA243072-05

Towards rational design of combination therapeutic targets

National Institutes of Health

Grant: 1U01CA232486-01

Multispecific targeting incorporating cytokine receptor pathways in high risk pediatric acute leukemias to improve durability of adoptive cell therapy-induced remissions

NCI NIH HHS

Grant: R37 CA262362

NCI NIH HHS

Grant: T32 CA009615

greenLicense: CC BY NC ND

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/08/16/2023.02.19.529123.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.02.19.529123

repositoryhttps://doi.org/10.1101/2023.02.19.529123

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37645778

Fields of Study

CAR-T cell therapy researchCancer Immunotherapy and BiomarkersT-cell and B-cell Immunology0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Translation (biology)RNA splicingMessenger RNAUntranslated regionAlternative splicingThree prime untranslated regionComputational biologyComputer scienceBiologyGeneGeneticsRNAEpstein-Barr Virus InfectionsHerpesvirus 4, HumanImmunobiology and ImmunotherapyAntigens, CD20Protein BiosynthesisNeoplasmsHumansProtein IsoformsRNA, MessengerImmunotherapy5' Untranslated Regions

Sustainable Development Goals

SDG 0: Good health and well-being