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Logic-based mechanistic machine learning on high-content images reveals how drugs differentially regulate cardiac fibroblasts

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.01.530599Source: DataRank Database

Logic-based mechanistic machine learning on high-content images reveals how drugs differentially regulate cardiac fibroblasts is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (20)IDs (PubMed, OpenAlex)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Steven L. Christiansen ORCID,Kristen M. Naegle ORCID,Jeffrey J. Saucerman ORCID,Anders R. Nelson ORCID

Live enrichment

PubMed:36909540 OpenAlex:https://openalex.org/W4323074469

National Institutes of Health

Grant: 1S10OD021723-01A1

Operetta CLS High-content Imaging System

National Institutes of Health

Grant: 5R01HL160665-02

Computational and Experimental Modeling of Cardiomyocyte Proliferation

National Institutes of Health

Grant: 5R01HL137755-03

Systems Pharmacology Model for Spatial Control of Cardiac Fibrosis

National Institutes of Health

Grant: 3R01HL162925-03S1

Diversity Supplement: Systems Pharmacology Model of Cardiac Hypertrophy

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/03/02/2023.03.01.530599.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.03.01.530599

repositoryhttps://doi.org/10.1101/2023.03.01.530599

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36909540

Fields of Study

Cell Image Analysis TechniquesComputational Drug Discovery MethodsCardiac Fibrosis and Remodeling

Keywords

Content (measure theory)Computer scienceArtificial intelligenceCell biologyChemistryComputational biologyBiologyMathematicsMachine LearningPhosphatidylinositol 3-KinasesHumansBiological SciencesFibroblastsMyosinsFibrosisArticleActins

Sustainable Development Goals

SDG 0: Good health and well-being