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A general computational design strategy for stabilizing viral class I fusion proteins

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.16.532924Source: DataRank Database

A general computational design strategy for stabilizing viral class I fusion proteins is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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Enrichment:Funding (6 grants)OA: greenTopics (37)IDs (PubMed, OpenAlex)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Jiachen Huang ORCID,Miriã F. Criado ORCID,Avik Banerjee ORCID,S. Mark Tompkins ORCID,Jarrod J. Mousa ORCID

Live enrichment

PubMed:36993551 OpenAlex:https://openalex.org/W4327862075

National Institutes of Health

Grant: 1R01AI140245-01

Design of Antivirals and Immunogens Targeting Paramyxoviruses

National Institutes of Health

Grant: 1R01AI143865-01A1

Structural and mechanistic insights into antibody neutralization of human metapneumovirus

NIAID NIH HHS

Grant: 75N93021C00018

NIAID NIH HHS

Grant: HHSN272201400004C

NIAID NIH HHS

Grant: R01 AI140245

NIAID NIH HHS

Grant: R01 AI143865

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/03/17/2023.03.16.532924.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.03.16.532924

repositoryhttps://doi.org/10.1101/2023.03.16.532924

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36993551

Fields of Study

Respiratory viral infections researchViral Infections and Outbreaks ResearchInfluenza Virus Research Studies0301 basic medicine03 medical and health sciences

Keywords

FusionFusion proteinComputational biologyVirusNative stateLipid bilayer fusionConformational changeViral proteinRational designBiologyBiophysicsVirologyCell biologyRecombinant DNABiochemistryGeneGeneticsVaccinesProtein ConformationScienceQ500Antibodies, ViralAntibodies, NeutralizingAntibodiesArticleMiceMedicine and Health SciencesAnimalsViralNeutralizingViral Fusion Proteins

Sustainable Development Goals

SDG 3: 3. Good health

A general computational design strategy for stabilizing viral class I fusion proteins

FAIR Checklist

Authors (7)

Funding (6 grants)

Open Access

Topics

Annotations (Europe PMC)