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Highly specific σ 2 R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.11.536439Source: DataRank Database

Highly specific σ 2 R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (31)IDs (PubMed, OpenAlex)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

James J. Sahn,Hongfen Yang ORCID,Eric T. David ORCID,Stephanie Shiers ORCID,Marisol Mancilla Moreno ORCID

Live enrichment

PubMed:37090527 OpenAlex:https://openalex.org/W4365149130

Natural Sciences and Engineering Research Council of Canada

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1R61NS127271-01A1

Planning Study for the Development of Sigma 2 ligands as Analgesics

National Institutes of Health

Grant: 1S10OD021508-01

Bruker AVANCE III HD 500 MHz NMR

NIDDK NIH HHS

Grant: R01 DK134893

NINDS NIH HHS

Grant: R61 NS127271

NIH HHS

Grant: S10 OD021508

greenLicense: cc-by-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/04/11/2023.04.11.536439.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.04.11.536439

repositoryhttps://doi.org/10.1101/2023.04.11.536439

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37090527

Fields of Study

Pharmacological Receptor Mechanisms and EffectsNeuropeptides and Animal PhysiologyReceptor Mechanisms and Signaling03 medical and health sciences0302 clinical medicine

Keywords

Neuropathic painDorsal root ganglionNeuroscienceSNiNociceptionKnockout mouseNociceptorNerve injuryPharmacologyMedicineHyperalgesiaNeuriteReceptorChemistrySensory systemInternal medicinePsychologyIn vitroBiochemistryArticleISRSigma 2 receptorTMEM97drug discoverypainσ2 receptor

Sustainable Development Goals

SDG 0: Good health and well-being