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Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.04.539492Source: DataRank Database

Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)OA: greenTopics (29)IDs (PubMed, OpenAlex)

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Authors (7)

Ramizah Syahirah,Sandeep K. Ravala ORCID,Yu‐Chen Yen ORCID,Thomas Klose ORCID,Qing Deng ORCID

Live enrichment

PubMed:37205329 OpenAlex:https://openalex.org/W4372348194

National Institutes of Health

Grant: 5R01CA221289-03

GPCR - Linked RhoGEFs in Tumor Growth and Metastasis

National Institutes of Health

Grant: 3R35GM119787-05S1

Role of microRNAs in neutrophil migration

National Institutes of Health

Grant: 1R01CA254402-01

Regulation of the metastasis promoting chemokine receptor ACKR3 by GPCR kinases, Gβγ and arrestins

NIGMS NIH HHS

Grant: R35 GM119787

NCI NIH HHS

Grant: R01 CA221289

NCI NIH HHS

Grant: R01 CA254402

NHLBI NIH HHS

Grant: R01 HL071818

NCI NIH HHS

Grant: P30 CA023168

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/05/05/2023.05.04.539492.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.05.04.539492

repositoryhttps://doi.org/10.1101/2023.05.04.539492

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37205329

Fields of Study

Protein Kinase Regulation and GTPase SignalingChronic Lymphocytic Leukemia ResearchGlycosylation and Glycoproteins Research0301 basic medicine03 medical and health sciences

Keywords

Phosphoinositide 3-kinaseBasis (linear algebra)Cell biologyChemistryBiologyMathematicsSignal transductionPI3K/AKT/mTOR pathwayGeometryModels, MolecularBinding SitesNeutrophilsProtein ConformationGTP-Binding Protein beta SubunitsCryoelectron MicroscopyArticleEnzyme ActivationAllosteric RegulationGTP-Binding Protein gamma SubunitsAnimalsClass Ib Phosphatidylinositol 3-KinaseHumansZebrafishProtein Binding