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Conformational Tuning Shapes the Balance between Functional Promiscuity and Specialization in Paralogous Plasmodium Acyl-CoA Binding Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.12.540612Source: DataRank Database

Conformational Tuning Shapes the Balance between Functional Promiscuity and Specialization in Paralogous Plasmodium Acyl-CoA Binding Proteins is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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Enrichment:Funding (1 grants)OA: greenTopics (27)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (7)

Westley Pawloski ORCID,Dhruv Kumar Chaurasiya ORCID,N. Srilatha,Sonal Agarwal,David Fushman ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W4376611724

National Science Foundation

Grant: 1040158

MRI: Acquisition of 800 MHz NMR Spectrometer to Strengthen Research in Science and Engineering at UMCP

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/05/13/2023.05.12.540612.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.05.12.540612

repositoryhttps://doi.org/10.1101/2023.05.12.540612

https://doi.org/10.1021/acs.biochem.3c00449

Fields of Study

Protein Structure and DynamicsRNA and protein synthesis mechanismsEnzyme Structure and Function0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

CooperativityAffinitiesCooperative bindingSequence (biology)BiologyFunctional divergenceBiophysicsPlasma protein bindingMolecular dynamicsBinding siteEvolutionary biologyChemistryGeneticsBiochemistryGeneComputational chemistryDiazepam Binding InhibitorPlasmodium falciparumMolecular ConformationProteinsAcyl Coenzyme A

Sustainable Development Goals

SDG 0: Good health and well-being