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Cisplatin Induces BDNF Downregulation in Middle-Aged Female Rat Model while BDNF Enhancement Attenuates Cisplatin Neurotoxicity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.15.540850Source: DataRank Database

Cisplatin Induces BDNF Downregulation in Middle-Aged Female Rat Model while BDNF Enhancement Attenuates Cisplatin Neurotoxicity is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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Enrichment:Funding (6 grants)OA: greenTopics (58)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (5)

Diana C. Pearre,Maureen T. Cruz,Kaijun Di ORCID,Daniela A. Bota ORCID,Naomi Lomeli ORCID

Live enrichment

PubMed:37293048 OpenAlex:https://openalex.org/W4377024465

National Institutes of Health

Grant: 5T32NS082174-05

Training Program in Stem Cell Translational Medicine for Neurological Disorders

National Institutes of Health

Grant: 5TL1TR001415-04

Institute for Clinical and Translational Science

National Institutes of Health

Grant: 3UL1TR001414-06S1

THE SEARCH FOR COVID-19 PREVENTION AND CURE: ADDRESSING THE CRITICAL ROLE OF INNATE/ADAPTIVE IMMUNITY BY INTEGRATING NOVEL INFORMATICS, TRANSLATIONAL TECHNOLOGIES, AND ONGOING CLINICAL TRIAL RESEARCH

National Institutes of Health

Grant: 3P30CA062203-27S1

Clinical Trial Advancement and Development for Sarcomas

National Institutes of Health

Grant: 5K08NS072234-03

Mechanisms of Chemotherapy Induced Cognitive Defects

National Institutes of Health

Grant: 5R01CA263806-03

Targeting p38/JNK MAPK to ameliorate cisplatin-induced adverse sequelae on the nervous system

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/05/17/2023.05.15.540850.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.05.15.540850

repositoryhttp://dx.doi.org/10.1101/2023.05.15.540850

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37293048

Fields of Study

Cancer-related cognitive impairment studiesGlioma Diagnosis and TreatmentCancer Treatment and Pharmacology03 medical and health sciences0302 clinical medicine

Keywords

CisplatinNeurotrophic factorsNeuroprotectionBrain-derived neurotrophic factorNeurogenesisHippocampal formationHippocampusMedicineInternal medicineEndocrinologyNeurotoxicityNeurosciencePsychologyOncologyChemotherapyToxicityReceptorAgingWomen's Health (rcdc)Biological Psychology610NeurodegenerativeAcquired Cognitive Impairment (rcdc)Basic Behavioral and Social ScienceRare Diseases (rcdc)Aging (rcdc)Rare DiseasesOvarian Cancer (rcdc)Brain Disorders (rcdc)Behavioral and Social ScienceAcquired Cognitive Impairment2.1 Biological and endogenous factors32 Biomedical and Clinical Sciences (for-2020)Neurosciences (rcdc)CancerNeurodegenerative (rcdc)Cancer (rcdc)Biomedical and Clinical Sciences52 Psychology (for-2020)Neurological (hrcs-hc)Neurosciences6002.1 Biological and endogenous factors (hrcs-rac)Cancer (hrcs-hc)Ovarian CancerBrain DisordersMental health (hrcs-hc)Neurological5202 Biological Psychology (for-2020)Women's HealthMental healthBasic Behavioral and Social Science (rcdc)Behavioral and Social Science (rcdc)

Sustainable Development Goals

SDG 0: Gender equality