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A Non-Coding Variant in SLC15A4 Modulates Enhancer Activity and Lysosomal Deacidification Linked to Lupus Susceptibility

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.28.551056Source: DataRank Database

A Non-Coding Variant in SLC15A4 Modulates Enhancer Activity and Lysosomal Deacidification Linked to Lupus Susceptibility is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (3 grants)OA: greenTopics (28)IDs (PubMed, OpenAlex)Annotations (1)SDGs (2)

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Authors (6)

Guru Prashad Maiti,Harikrishna Reddy-Rallabandi,Mehdi Fazel‐Najafabadi ORCID,Loren L. Looger ORCID,Swapan K. Nath ORCID

Live enrichment

PubMed:37546883 OpenAlex:https://openalex.org/W4385387827

National Institutes of Health

Grant: 1R21AI144829-01A1

Role of Two Interferon Regulatory Genes in Lupus

National Institutes of Health

Grant: 5R01AI172255-02

Contributions of autophagy-related genes in lupus

National Institutes of Health

Grant: 1R21AI168943-01

Connecting the gap between GWAS and functional targets for lupus susceptibility

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/09/02/2023.07.28.551056.full.pdf

GREENhttps://www.biorxiv.org/content/biorxiv/early/2023/09/02/2023.07.28.551056.full.pdf

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/09/02/2023.07.28.551056.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.07.28.551056

repositoryhttps://doi.org/10.1101/2023.07.28.551056

Fields of Study

Retinoids in leukemia and cellular processesUbiquitin and proteasome pathwaysinterferon and immune responsesMedicineBiology0301 basic medicine03 medical and health sciences

Keywords

EnhancerCoding (social sciences)Systemic lupus erythematosusComputational biologyChemistryBiologyBiochemistryMedicineGeneInternal medicineMathematicsStatisticsGene expressionCRISPRLysosomal acidificationChIP-qPCRSLC15A4610LupusLuciferase576

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being