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Water and chloride as allosteric inhibitors in WNK kinase osmosensing

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.29.555411Source: DataRank Database

Water and chloride as allosteric inhibitors in WNK kinase osmosensing is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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Enrichment:Funding (2 grants)OA: greenTopics (35)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (5)

Radha Akella ORCID,John M. Humphreys ORCID,Haixia He ORCID,Elizabeth J. Goldsmith ORCID,Liliana R. Teixeira ORCID

Live enrichment

PubMed:37693587 OpenAlex:https://openalex.org/W4386315022

National Institutes of Health

Grant: 8P41GM103393-33

A Synchroton Radiation Structural Biology Resource

National Institutes of Health

Grant: 2R01DK110358-07A1

Regulation of WNK signaling by potassium and Mo25: structure, function and physiology

Influential Citations

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/08/31/2023.08.29.555411.full.pdf

GREENhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491171

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/08/31/2023.08.29.555411.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.08.29.555411

repositoryhttps://doi.org/10.1101/2023.08.29.555411

Fields of Study

Ion Transport and Channel RegulationCalcium signaling and nucleotide metabolismMetabolism, Diabetes, and CancerBiologyMedicineChemistry0301 basic medicine03 medical and health sciences

Keywords

Allosteric regulationChemistryKinasePharmacologyBiochemistryBiologyEnzymeQH301-705.5ScienceStructural Biology and Molecular BiophysicswaterQRProtein Serine-Threonine KinasesosmosensorCrystallography, X-RayWNK3OsmoregulationChloridesWNK Lysine-Deficient Protein Kinase 1MedicineHumansBiology (General)PhosphorylationWNK1crystallographychloride ion

Sustainable Development Goals

SDG 0: Clean water and sanitation

Water and chloride as allosteric inhibitors in WNK kinase osmosensing

FAIR Checklist

Authors (5)

Funding (2 grants)

Impact

Open Access

Topics