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Targeting YAP mechanosignaling to ameliorate stiffness-induced Schlemm’s canal cell pathobiology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.08.556840Source: DataRank Database

Targeting YAP mechanosignaling to ameliorate stiffness-induced Schlemm’s canal cell pathobiology is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (33)IDs (PubMed, OpenAlex)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Megan Kuhn,Ruth A. Kelly ORCID,Ayushi Singh ORCID,Kavipriya Kovai Palanivel,Izzy Salama

Live enrichment

PubMed:37781615 OpenAlex:https://openalex.org/W4386588398

National Institutes of Health

Grant: 5P30EY005722-27

P30 - Center Core Grant for Vision Research

National Institutes of Health

Grant: 5R01EY022359-07

eNOS-Dependent Mechanoregulation of Intraocular Pressure

National Institutes of Health

Grant: 5K08EY031755-03

Investigating mechanosensation in the glaucomatous optic nerve head

National Institutes of Health

Grant: 5R01EY034096-04

Role of cellular memory in glaucoma.

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/09/10/2023.09.08.556840.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.09.08.556840

repositoryhttps://doi.org/10.1101/2023.09.08.556840

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37781615

Fields of Study

Hippo pathway signaling and YAP/TAZGlaucoma and retinal disordersFibroblast Growth Factor Research0301 basic medicine03 medical and health sciences

Keywords

Trabecular meshworkMechanotransductionGlaucomaExtracellular matrixStiffeningSchlemm's canalCell biologyMyocilinCellChemistryPathogenesisOphthalmologyAnatomyMedicinePathologyBiologyMaterials scienceYAP-Signaling ProteinsCell Cycle ProteinsMechanotransduction, CellularArticleMiceTranscriptional Coactivator with PDZ-Binding Motif ProteinsTrans-ActivatorsAnimalsHumansTranscription FactorsAdaptor Proteins, Signal Transducing

Sustainable Development Goals

SDG 0: Clean water and sanitation