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Identifying latent genetic interactions in genome-wide association studies using multiple traits

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.11.557155Source: DataRank Database

Identifying latent genetic interactions in genome-wide association studies using multiple traits is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)OA: greenTopics (73)IDs (PubMed, OpenAlex)

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Authors (6)

Shijia Bian ORCID,Aliza P. Wingo ORCID,Thomas S. Wingo ORCID,David J. Cutler ORCID,Michael P. Epstein ORCID

Live enrichment

PubMed:37745553 OpenAlex:https://openalex.org/W4386715277

National Institutes of Health

Grant: 1RF1AG071170-01

Quantitative Genetic Models for Exploring Missing Heritability of Alzheimer's Disease

National Institutes of Health

Grant: 1R01AG079170-01

Air pollution and early signs of dementia

National Institutes of Health

Grant: 1R01AG072120-01A1

A brain multi-omic approach to identify key molecular drivers of neuropsychiatric symptoms in Alzheimer's dementia

National Institutes of Health

Grant: 5R01AG075827-02

Integrative genomic, transcriptomic, and proteomic analyses to investigate sex-specific differences in Alzheimer's Disease

NIA NIH HHS

Grant: R01 AG072120

NIA NIH HHS

Grant: R01 AG075827

NIA NIH HHS

Grant: R01 AG079170

NIA NIH HHS

Grant: RF1 AG071170

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/09/13/2023.09.11.557155.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.09.11.557155

repositoryhttps://doi.org/10.1101/2023.09.11.557155

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37745553

Fields of Study

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and AnimalsBioinformatics and Genomic Networks0301 basic medicine03 medical and health sciences

Keywords

HeritabilityTraitGenome-wide association studyBiologyGenetic correlationBiobankMissing heritability problemPleiotropyQuantitative trait locusGenetic associationCovariateGenetic architectureGeneticsUnivariateGenetic variationGenotypeSingle-nucleotide polymorphismGeneMultivariate statisticsComputer scienceMachine learningPhenotypeMultifactorial InheritanceMethodQH426-4703105 Genetics (for-2020)0604 Genetics (for)Models1103 Clinical Sciences (for)Obesity (mesh)2.1 Biological and endogenous factorsGenetic Predisposition to Disease (mesh)Humans (mesh)RGenetic PleiotropySingle NucleotideBiological SciencesPhenotype (mesh)Multifactorial Inheritance (mesh)MedicineGenome-Wide Association Study (mesh)Quantitative Trait Loci (mesh)Single Nucleotide (mesh)Heritable (mesh)Clinical SciencesQuantitative Trait Loci610Polymorphism, Single NucleotideArticleQuantitative TraitQuantitative Trait, HeritableGeneticHumansGenetic Predisposition to DiseaseObesityPolymorphismGenetic Pleiotropy (mesh)HeritableObesity (rcdc)31 Biological Sciences (for-2020)Models, GeneticGenetics (rcdc)Human GenomeEpistasis, Genetic2.1 Biological and endogenous factors (hrcs-rac)Human Genome (rcdc)EpistasisGenetic (mesh)