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Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.20.563371Source: DataRank Database

Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)OA: greenTopics (27)IDs (PubMed, OpenAlex)

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Authors (5)

Akane Osa,Oscar W. Huang,Ingrid E. Wertz ORCID,Daniel K. Nomura ORCID,Seong Ho Hong ORCID

Live enrichment

PubMed:37904950 OpenAlex:https://openalex.org/W4387861039

National Institutes of Health

Grant: 1R35CA263814-01A1

Tackling Undruggable Cancer Targets using Chemoproteomic Platforms

National Institutes of Health

Grant: 1S10OD024998-01

Acquisition of a Cryoprobe and Related Accessories for a 600 MHz NMR Spectrometer to Support Health Research Activities at the University of California, Berkeley

National Science Foundation

Grant: 2127788

MFB: Developing Next-Generation Approaches to Targeted Protein Degradation

National Institutes of Health

Grant: 5R01CA240981-07

Harnessing E3 Ligases for Cancer Therapy

NCI NIH HHS

Grant: R01 CA240981

NCI NIH HHS

Grant: R35 CA263814

NIH HHS

Grant: S10 OD024998

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/11/02/2023.10.20.563371.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.10.20.563371

repositoryhttps://doi.org/10.1101/2023.10.20.563371

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37904950

Fields of Study

Protein Degradation and InhibitorsUbiquitin and proteasome pathwaysCAR-T cell therapy research

Keywords

CullinSkp1Signal transducing adaptor proteinUbiquitin ligaseUbiquitinF-box proteinDegradation (telecommunications)DDB1Cell biologyProtein degradationChemistryComputer scienceBiologyBiochemistrySignal transductionArticleARBRD4CUL1activity-based protein profilingandrogen receptorchemoproteomicscovalenttargeted protein degradation