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Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.17.567640Source: DataRank Database

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 3 times.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)OA: greenTopics (39)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (16)

Kip D. Zimmerman ORCID,Sobha Puppala ORCID,Jeannie Chan ORCID,Hillary F. Huber ORCID,Ge Li ORCID

Live enrichment

PubMed:38014295 OpenAlex:https://openalex.org/W4388792865

National Institutes of Health

Grant: 3P51OD011133-22S2

Nonhuman Primate model of age-related cognitive decline and dementias

European Commission

Grant: 101080329

DE-RISKING METABOLIC, ENVIRONMENTAL AND BEHAVIORAL DETERMINANTS OF OBESITY IN CHILDREN, ADOLESCENTS AND YOUNG ADULTS

European Commission

Grant: 857524

Multidisciplinary Institute of Ageing - Portugal

Fundação para a Ciência e a Tecnologia, I.P.

Grant: LA/P/0058/2020

Center for Innovative Biomedicine and Biotechnology - Associate Laboratory

National Institutes of Health

Grant: 1U19AG057758-01A1

Womb to Tomb: Developmental Programming and Aging Interactions in Primates

NIH HHS

Grant: P51 OD011133

NIA NIH HHS

Grant: U19 AG057758

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/11/18/2023.11.17.567640.full.pdf

GREENhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680868

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/11/18/2023.11.17.567640.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.11.17.567640

repositoryhttps://doi.org/10.1101/2023.11.17.567640

Fields of Study

Proteoglycans and glycosaminoglycans researchMetabolomics and Mass Spectrometry StudiesMetabolism, Diabetes, and CancerBiologyMedicine0303 health sciences03 medical and health sciences

Keywords

Downregulation and upregulationBiologyGlycosaminoglycanMetabolic pathwayCell biologyTranscriptomeOxidative phosphorylationEndocrinologyGlycolysisInternal medicineCitric acid cycleBiochemistryMetabolismGene expressionMedicineGeneAgingcardiac hypertrophyScienceMyocardiumQHexosaminesArticleBiosynthetic Pathwayscardiac metabolismaging; cardiac hypertrophy; cardiac metabolism; cardiovascular disease; glycosaminoglycancardiovascular diseaseAnimalsFemaleResearch ArticleGlycosaminoglycansPapio

Sustainable Development Goals

SDG 0: Good health and well-being