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Loss of cardiac PFKFB2 drives Metabolic, Functional, and Electrophysiological Remodeling in the Heart

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.22.568379Source: DataRank Database

Loss of cardiac PFKFB2 drives Metabolic, Functional, and Electrophysiological Remodeling in the Heart is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (33)IDs (PubMed, OpenAlex)SDGs (1)

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Open Access

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Reusable (0/3)

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Authors (11)

Satoshi Matsuzaki ORCID,Atul Pranay ORCID,Brooke L. Loveland,Albert Batushansky ORCID,Maria F. Mendez Garcia

Live enrichment

PubMed:38045353 OpenAlex:https://openalex.org/W4388941329

National Institutes of Health

Grant: 1P30AG050911-01

Integrative Redox Biology Core

National Institutes of Health

Grant: 1R24GM137786-01

IDeA National Resource for Quantitative Proteomics

National Institutes of Health

Grant: 3P20GM103447-17S1

Oklahoma IDeA Network of Biomedical Research Excellence

National Institutes of Health

Grant: 5R01HL160955-02

Increasing glycolysis in the diabetic heart is cardioprotective and improves glucose tolerance

National Institutes of Health

Grant: 3P20GM139763-03S1

Center for Cellular Metabolism Research in Oklahoma

greenLicense: CC BY NC

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/11/23/2023.11.22.568379.1.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.11.22.568379

repositoryhttps://doi.org/10.1101/2023.11.22.568379

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38045353

Fields of Study

Cancer, Hypoxia, and MetabolismDiet, Metabolism, and DiseaseCardiovascular Function and Risk Factors0303 health sciences03 medical and health sciences

Keywords

GlycolysisInternal medicineEndocrinologyPentose phosphate pathwayPyruvate dehydrogenase complexBiologyDownregulation and upregulationCardiac function curveMitochondrionCarbohydrate metabolismMetabolismHeart failureBiochemistryEnzymeMedicineProteomicsPhosphofructokinase-2electrocardiographyMiceGlucoseRC666-701echocardiographyDiseases of the circulatory (Cardiovascular) systemAnimalsInsulinMyocytes, CardiacPyruvatesOriginal Research

Sustainable Development Goals

SDG 0: Good health and well-being