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Multivariate analysis of metabolic state vulnerabilities across diverse cancer contexts reveals synthetically lethal associations

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.28.569098Source: DataRank Database

Multivariate analysis of metabolic state vulnerabilities across diverse cancer contexts reveals synthetically lethal associations is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)OA: greenTopics (34)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (5)

Audrey D. Kidd,Ying Jiang ORCID,Hui Zong ORCID,Mohammad Fallahi‐Sichani ORCID,Cara Abecunas ORCID

Live enrichment

PubMed:38076921 OpenAlex:https://openalex.org/W4389154332

National Institutes of Health

Grant: 5T32GM145443-04

Interdisciplinary Training in Systems & Biomolecular Data Science

National Institutes of Health

Grant: 7R35GM133404-02

Decoding the Logic of Cellular Signaling Through the Integration of Dynamic, Single-Cell and Multiplexed Methods

National Institutes of Health

Grant: 1R21NS125479-01A1

Discover the signaling basis for OPC homeostasis

National Institutes of Health

Grant: 1U54CA274499-01

Systems Analysis of Stress-adapted Cancer Organelles (SASCO) Center

National Institutes of Health

Grant: 5R01CA249229-04

Linking Genetic, Epigenetic and Signaling Mechanisms of Oncogene Addiction

NCI NIH HHS

Grant: R01 CA249229

NIGMS NIH HHS

Grant: R35 GM133404

NINDS NIH HHS

Grant: R21 NS125479

NCI NIH HHS

Grant: U54 CA274499

NIGMS NIH HHS

Grant: T32 GM145443

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/11/29/2023.11.28.569098.full.pdf

GREENhttps://www.biorxiv.org/content/biorxiv/early/2023/11/29/2023.11.28.569098.full.pdf

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/11/29/2023.11.28.569098.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.11.28.569098

repositoryhttps://doi.org/10.1101/2023.11.28.569098

Fields of Study

Cancer, Hypoxia, and MetabolismBioinformatics and Genomic NetworksMetabolomics and Mass Spectrometry StudiesBiologyMedicine03 medical and health sciences0302 clinical medicine

Keywords

Context (archaeology)Computational biologyBiologyCancerPTENCancer cellMetabolomicsBioinformaticsPhenotypeCancer researchGeneticsGenePI3K/AKT/mTOR pathwaySignal transductionQH301-705.5CP: MetabolismArticleOxidative PhosphorylationMitochondriaNeoplasmsCell Line, TumorMultivariate AnalysisHumansAnimalsBiology (General)Synthetic Lethal MutationsCP: Cancer

Sustainable Development Goals

SDG 0: Good health and well-being