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Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.04.569845Source: DataRank Database

Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3 is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

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Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)OA: greenTopics (22)IDs (PubMed, OpenAlex)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Andreas Krämer ORCID,Benjamin G. Strickland ORCID,Jeffery L. Smith ORCID,Rebekah J. Dickmander ORCID,Nathaniel J. Moorman ORCID

Live enrichment

PubMed:38106118 OpenAlex:https://openalex.org/W4389303385

European Commission

Grant: 875510

EUbOPEN: Enabling and Unlocking biology in the OPEN

National Institutes of Health

Grant: 1U24DK116204-01

Illuminating Function of the Understudied Druggable Kinome

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/12/05/2023.12.04.569845.full.pdf

GREENhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10723276

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/12/05/2023.12.04.569845.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.12.04.569845

repositoryhttps://doi.org/10.1101/2023.12.04.569845

Fields of Study

Cancer Mechanisms and TherapyPeptidase Inhibition and AnalysisCancer therapeutics and mechanismsBiologyMedicineChemistry01 natural sciences0104 chemical sciences

Keywords

SelectivitySubstituentChemistryStereochemistryPyrazineCombinatorial chemistryStructure–activity relationshipBiochemistryIn vitroStructure-Activity RelationshipPyrazinesBenzoatesAntiviral AgentsArticle

Sustainable Development Goals

SDG 3: 3. Good health