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Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.01.573836Source: DataRank Database

Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)OA: greenTopics (36)IDs (PubMed, OpenAlex)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Kevin Cho ORCID,Haluk Lacin ORCID,Yi Zhun Zhu ORCID,Jose T DiPaola,Beth Wilson

Live enrichment

PubMed:38260379 OpenAlex:https://openalex.org/W4390656828

National Institutes of Health

Grant: NS036570

National Institutes of Health

Grant: NS122903

National Institutes of Health

Grant: ES2028365

National Institutes of Health

Grant: 5R01NS036570-03

NEURAL DETERMINATION IN DROSOPHILA

National Institutes of Health

Grant: 5R01NS122903-04

Developmental and Genetic Basis of Neural Circuit Formation and Behavior

National Institutes of Health

Grant: 2P30DK020579-36

Diabetes Research Center

NCI NIH HHS

Grant: P30 CA091842

NIDDK NIH HHS

Grant: P30 DK020579

NINDS NIH HHS

Grant: R01 NS036570

NINDS NIH HHS

Grant: R01 NS122903

greenLicense: cc-by-nc

repositoryhttps://doi.org/10.1101/2024.01.01.573836

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.01.01.573836

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38260379

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10802327

Fields of Study

Lysosomal Storage Disorders ResearchSphingolipid Metabolism and SignalingRNA regulation and disease0301 basic medicine03 medical and health sciences

Keywords

Endoplasmic reticulumCell biologyNeurodegenerationCeramideSphingolipidGene knockdownBiologyUnfolded protein responseLipid signalingInternal medicineBiochemistryApoptosisImmunologyInflammationMedicineDiseaseDrosophila melanogasterAnimalsHomeostasisDrosophila ProteinsLipid DropletsOxidoreductasesCeramidesNeurogliaArticleDevelopmental BiologyDEGS1glialeukodystrophylipid dropletsphingolipids