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Dissecting quantitative trait nucleotides by saturation genome editing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.02.577784Source: DataRank Database

Dissecting quantitative trait nucleotides by saturation genome editing is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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Enrichment:Funding (3 grants)OA: greenTopics (27)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (11)

Justin Smith ORCID,Shengdi Li ORCID,Sibylle C. Vonesch ORCID,Michelle Nguyen ORCID,Wallace T. Burnett ORCID

Live enrichment

PubMed:38352467 OpenAlex:https://openalex.org/W4391511942

National Institutes of Health

Grant: 5R01GM121932-04

Capturing the phenotypic landscape of single-nucleotide variation via systematic genome editing

National Institutes of Health

Grant: 1R01HG012446-01

EDGE CMT: Dissecting complex traits in wild isolates of yeast by high-throughput genome editing

European Commission

Grant: 742804

Dissecting quantitative traits and their underlying genetic interactions via systematic genome editing

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/02/02/2024.02.02.577784.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.02.02.577784

repositoryhttps://doi.org/10.1101/2024.02.02.577784

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38352467

Fields of Study

CRISPR and Genetic EngineeringEvolution and Genetic DynamicsRNA and protein synthesis mechanisms0301 basic medicine03 medical and health sciences

Keywords

Genome editingBiologyGenomeComputational biologyCRISPRGeneticsCas9Genebarcode sequencing (Bar-seq)quantitative geneticsDNA repairdonor DNAdonor recruitmentArticlecomplex traitshomology-directed repair (HDR)MS2 coat protein (MCP)quantitative trait lociCRISPR genome editingforkhead-associated (FHA) domainretronplasmid assembly

Sustainable Development Goals

SDG 0: Life in Land