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Three Prime Repair Exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural and conformational properties

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.19.585766Source: DataRank Database

Three Prime Repair Exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural and conformational properties is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)OA: greenTopics (19)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (9)

Purva Khodke ORCID,Muthukumar Balasubramaniam ORCID,Benem-Orom Davids,Thomas Hollis ORCID,Jamaine Davis ORCID

Live enrichment

PubMed:38562877 OpenAlex:https://openalex.org/W4393013188

NIAID NIH HHS

Grant: R01 AI136740

NIAID NIH HHS

Grant: R01 AI162694

NIDA NIH HHS

Grant: R01 DA057204

NIAID NIH HHS

Grant: P30 AI117970

NIAID NIH HHS

Grant: P30 AI110527

NIAID NIH HHS

Grant: R25 AI164610

NIAID NIH HHS

Grant: R01 AI170228

NIMHD NIH HHS

Grant: U54 MD007586

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/03/19/2024.03.19.585766.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.03.19.585766

repositoryhttps://doi.org/10.1101/2024.03.19.585766

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38562877

Fields of Study

HIV Research and TreatmentHIV/AIDS drug development and treatmentCRISPR and Genetic Engineering

Keywords

DNAExonucleaseEnzyme kineticsDNA clampBiophysicsKineticsChemistryDocking (animal)BiologyBiochemistryDNA polymeraseEnzymeActive sitePolymerase chain reactionReverse transcriptaseGene

Sustainable Development Goals

SDG 0: Good health and well-being