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Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.586364Source: DataRank Database

Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson’s disease is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:OA: greenTopics (16)IDs (PubMed, OpenAlex)

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Accessible (1/2)

Open Access

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Reusable (0/3)

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Authors (13)

Logan M. Glasstetter,Tiffany T. Jong,Abhijeet Kapoor ORCID,Sha Zhu ORCID,Yanping Zhu ORCID

Live enrichment

PubMed:38712038 OpenAlex:https://openalex.org/W4393235444

greenLicense: public-domain

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/03/27/2024.03.22.586364.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.03.22.586364

repositoryhttps://doi.org/10.1101/2024.03.22.586364

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38712038

Fields of Study

Lysosomal Storage Disorders ResearchCarbohydrate Chemistry and SynthesisCellular transport and secretion

Keywords

GlucocerebrosidaseDiseaseParkinson's diseaseMedicineInternal medicineGBA1Gaucher diseaseHiBiTParkinson’s diseasechemical genomicshigh-throughput screeninglysosomepharmacological chaperone