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IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.02.587608Source: DataRank Database

IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (27)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Sara Collins ORCID,Pavlina Chuntova ORCID,Trishna S. Patel ORCID,Takahide Nejo ORCID,Akane Yamamichi ORCID

Live enrichment

PubMed:38617245 OpenAlex:https://openalex.org/W4393903181

National Institutes of Health

Grant: 5R35NS105068-05

Preclinical development of breakthrough immunotherapy for brain tumors

National Institutes of Health

Grant: 5T32CA151022-07

Training Program in Translational Brain Tumor Research

National Institutes of Health

Grant: 5R25GM056847-10

Biomedical Science Research Career Enhancement Program

NIGMS NIH HHS

Grant: R25 GM056847

NINDS NIH HHS

Grant: R35 NS105068

NCI NIH HHS

Grant: T32 CA151022

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/04/03/2024.04.02.587608.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.04.02.587608

repositoryhttps://doi.org/10.1101/2024.04.02.587608

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38617245

Fields of Study

Immune cells in cancerGlioma Diagnosis and Treatmentinterferon and immune responses03 medical and health sciences0302 clinical medicine

Keywords

IRF8Cancer researchBiologyTumor microenvironmentReprogrammingGliomaImmune systemCD8MyeloidImmunotherapyT cellTumor antigenCytotoxic T cellImmunologyCellIn vitroTranscription factorArticleGlioblastomaImmunosuppressionMDSCRRV-mediated gene therapy

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being