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Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic morphine

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.15.589671Source: DataRank Database

Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic morphine is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0. It has been cited 1 time.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)OA: greenTopics (44)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (10)

Randi Foxall ORCID,Lindsey Felth,Soren Maret,Zachary Rosa,Anirudh Gaur ORCID

Live enrichment

PubMed:38659831 OpenAlex:https://openalex.org/W4394930725

National Institutes of Health

Grant: 1F31DA056222-01

The effect of biased agonism at the Mu-Opioid receptor on drug seeking behavior

National Institutes of Health

Grant: 2P20GM103506-06

Administrative Core

National Institutes of Health

Grant: 5R21DA049565-02

The Microbiome in opioid use and abuse

National Institutes of Health

Grant: 1R15DA058187-01A1

Probiotic neuroimmune modulation of morphine tolerance

NIDA NIH HHS

Grant: R15 DA058187

NIMH NIH HHS

Grant: T32 MH112507

NIDA NIH HHS

Grant: R21 DA049565

NIDA NIH HHS

Grant: F31 DA056222

NIGMS NIH HHS

Grant: P20 GM103506

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/04/17/2024.04.15.589671.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.04.15.589671

repositoryhttps://doi.org/10.1101/2024.04.15.589671

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38659831

Fields of Study

Gut microbiota and healthTryptophan and brain disordersStress Responses and Cortisol0301 basic medicine03 medical and health sciences

Keywords

DysbiosisButyrateGut floraDrug toleranceMorphineBiologyAnalgesicPain tolerancePharmacologyMedicineImmunologyInternal medicineThreshold of painMale610OpioidRC799-869Inbred C57BLArticleMiceAnimalsAnalgesicsanalgesic toleranceBacteriaProbioticsMicrobiota600opioid use disorderDiseases of the digestive system. GastroenterologyFecal Microbiota TransplantationFatty Acids, VolatileGastrointestinal MicrobiomeAnalgesics, OpioidMice, Inbred C57BLButyratesDisease Models, Animalinflammationshort-chain fatty acidResearch Paper

Sustainable Development Goals

SDG 0: Good health and well-being