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Mechanism and spectrum of inhibition of a 4’-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.22.590607Source: DataRank Database

Mechanism and spectrum of inhibition of a 4’-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: greenTopics (22)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (10)

Simon Walker ORCID,Egor P. Tchesnokov ORCID,Dana Kocíncová,Jared Pitts ORCID,Dustin S. Siegel ORCID

Live enrichment

PubMed:30945415 OpenAlex:https://openalex.org/W4395080033

National Institutes of Health

Grant: 1U19AI171292-01

RAPIDLY EMERGING ANTIVIRAL DRUG DEVELOPMENT INITIATIVE- AViDD CENTER (READDI-AC)

Canadian Institutes of Health Research

Grant: unidentified

unidentified

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/04/23/2024.04.22.590607.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.04.22.590607

repositoryhttps://doi.org/10.1101/2024.04.22.590607

https://doi.org/10.1016/j.jbc.2024.107514

Fields of Study

Viral gastroenteritis research and epidemiologyRespiratory viral infections researchBacteriophages and microbial interactions0301 basic medicine03 medical and health sciences

Keywords

Mechanism (biology)RNANucleotidePolymeraseRNA-dependent RNA polymeraseVirologyChemistryBiologyGeneticsGenePhysicsNucleotidesHumansRNA VirusesMetapneumovirusAntiviral AgentsResearch Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being