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Neuroendocrine Prostate Cancer Drivers SOX2 and BRN2 Confer Differential Responses to Imipridones ONC201, ONC206, and ONC212 in Prostate Cancer Cell Lines

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.28.610184Source: DataRank Database

Neuroendocrine Prostate Cancer Drivers SOX2 and BRN2 Confer Differential Responses to Imipridones ONC201, ONC206, and ONC212 in Prostate Cancer Cell Lines is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: greenTopics (23)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (6)

Praveen R. Srinivasan ORCID,Maximilian Pinho-Schwermann ORCID,William MacDonald ORCID,Elizabeth Ding,Wafik S. El‐Deiry ORCID

Live enrichment

PubMed:39257809 OpenAlex:https://openalex.org/W4402035598

National Institutes of Health

Grant: 3R01CA173453-10S1

ONC201/TIC10 Anti-tumor Effect Through Regulation of the TRAIL pathway

NCI NIH HHS

Grant: R01 CA173453

greenLicense: cc-by-nc-nd

repositoryhttps://doi.org/10.1101/2024.08.28.610184

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.08.28.610184

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39257809

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11383667

Fields of Study

Prostate Cancer Treatment and ResearchPARP inhibition in cancer therapyReceptor Mechanisms and Signaling03 medical and health sciences0302 clinical medicine

Keywords

DU145LNCaPProstate cancerNeuroendocrine differentiationCancer researchSOX2CancerAndrogen deprivation therapyMedicineInternal medicineEndocrinologyBiologyTranscription factorArticleBRN2, SOX2ONC201ONC206ONC212

Sustainable Development Goals

SDG 0: Good health and well-being