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Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-induced lung injury

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.13.612775Source: DataRank Database

Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-induced lung injury is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (73)IDs (PubMed, OpenAlex)

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Authors (18)

Nathanael J. Spann ORCID,Wenxi Tang ORCID,Fenghua Zeng,John Lalith Charles Richard ORCID,Cadence Seymour

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W4402633564

National Institutes of Health

Grant: 1F32HL167318-01

Spatiotemporal Atlas of Cellular Networks and Ultrastructural States Mediating the Progression and Resolution of Pulmonary Fibrosis

National Institutes of Health

Grant: 1S10OD026929-01

Illumina NovaSeq 6000 Sequencing System

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 3P30CA023100-25S4

Specialized Cancer Center Support Grant

greenLicense: Springer Nature TDM

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/09/19/2024.09.13.612775.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.09.13.612775

repositoryhttps://doi.org/10.1101/2024.09.13.612775

https://doi.org/10.1038/s41590-025-02217-4

Fields of Study

Inflammation biomarkers and pathwaysRespiratory Support and MechanismsChronic Obstructive Pulmonary Disease (COPD) Research0303 health sciences03 medical and health sciences

Keywords

TREM2OxygenLungGenetic variationVariation (astronomy)Cell biologyChemistryBiologyReceptorInternal medicineMedicineGeneGeneticsPhysicsPrevention (rcdc)Inbred C57BL (mesh)Lung Injury (mesh)Low Birth Weight and Health of the Newborn (rcdc)Lung (rcdc)MiceReceptorsAnimals (mesh)Receptors, Immunologic32 Biomedical and Clinical Sciences (for-2020)3101 Biochemistry and cell biology (for-2020)Bronchopulmonary DysplasiaMice, KnockoutHumans (mesh)Membrane GlycoproteinsMice (mesh)Lung InjuryKnockout (mesh)3213 Paediatrics (for-2020)Newborn (mesh)Immunology (science-metrix)Signal TransductionPerinatal Period - Conditions Originating in Perinatal Period (rcdc)Immunologic (mesh)1107 Immunology (for)HyperoxiaArticleRare Diseases (rcdc)Preterm5.1 Pharmaceuticals (hrcs-rac)Membrane Glycoproteins (mesh)AnimalsHumansPediatric (rcdc)Genetic Variation (mesh)3204 Immunology (for-2020)Animal (mesh)Bronchopulmonary Dysplasia (mesh)ImmunityTumor Suppressor Protein p53 (mesh)2.1 Biological and endogenous factors (hrcs-rac)Hyperoxia (mesh)Lung (mesh)Immunity, InnateMice, Inbred C57BLDisease Models, AnimalAnimals, NewbornDisease ModelsOrphan Drug (rcdc)Signal Transduction (mesh)Oxygen (mesh)Innate (mesh)Tumor Suppressor Protein p53Neonatal Respiratory Distress (rcdc)