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DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.27.620508Source: DataRank Database

DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (42)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (7)

Hanaa Saleh ORCID,Ítalo de Araújo Castro,Adrianus C. M. Boon ORCID,Amelia K. Pinto ORCID,James D. Brien ORCID

Live enrichment

PubMed:39553933 OpenAlex:https://openalex.org/W4403855602

National Institutes of Health

Grant: 1R56AI150965-01A1

Harnessing ZBP1-driven cell death to improve influenza vaccine efficacy

National Institutes of Health

Grant: 5R01AI134862-04

Mechanisms of DDO Adjuvancy

National Institutes of Health

Grant: 3U01CA260541-02S1

SARS-CoV-2 correlates of protection in a Latino-origin population

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2024/10/29/2024.10.27.620508.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.10.27.620508

repositoryhttps://doi.org/10.1101/2024.10.27.620508

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39553933

Fields of Study

Influenza Virus Research Studiesinterferon and immune responsesImmune Response and Inflammation0301 basic medicine03 medical and health sciences0302 clinical medicine

Keywords

NucleoproteinImmune systemVirologyVirusImmunologyBiologyMessenger RNAGeneGeneticsCD8-Positive T-LymphocytesAntibodies, ViralMicrobiologyArticleMiceOrthomyxoviridae InfectionsAdjuvants, ImmunologicAnimalsAdjuvants, VaccineImmunity, CellularVaccines, SyntheticViral Core ProteinsRNA-Binding ProteinsNucleocapsid ProteinsAntibodies, NeutralizingQR1-502Immunity, HumoralMice, Inbred C57BLmRNA vaccineNucleoproteinsadjuvantsInfluenza VaccinesInfluenza A virusFemalemRNA Vaccinestype I IFNResearch Article

Sustainable Development Goals

SDG 0: Good health and well-beingSDG 0: Zero hunger