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The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.01.626216Source: DataRank Database

The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2024). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)OA: greenTopics (22)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Nalini R. Rao ORCID,Matthew Wright ORCID,Jeffrey N. Savas ORCID,Evangelos Kiskinis ORCID,Andrew C. Fleming ORCID

Live enrichment

PubMed:39651147 OpenAlex:https://openalex.org/W4404892803

NINDS NIH HHS

Grant: F31 NS132580

NINDS NIH HHS

Grant: R01 NS104219

NINDS NIH HHS

Grant: R21 NS131713

NIH HHS

Grant: S10 OD032464

greenLicense: cc-by

repositoryhttps://doi.org/10.1101/2024.12.01.626216

publisherhttps://syndication.highwire.org/content/doi/10.1101/2024.12.01.626216

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39651147

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11623670

Fields of Study

Heat shock proteins researchEndoplasmic Reticulum Stress and DiseaseResilience and Mental Health

Keywords

HSF1NeuroprotectionChaperone (clinical)Cell biologyBiologyCancer researchHsp70NeuroscienceHeat shock proteinMedicineGeneticsGeneAmyotrophic lateral sclerosis (ALS)DNAJC7HNRNPUchaperoneiPSC modelsmotor neuronsstress response

Sustainable Development Goals

SDG 0: Good health and well-being