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Computation model predicts Rho GTPase function with the Plexin Transmembrane receptor GAP activity on Rap1b via dynamic allosteric changes

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.03.13.643120Source: DataRank Database

Computation model predicts Rho GTPase function with the Plexin Transmembrane receptor GAP activity on Rap1b via dynamic allosteric changes is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (3 grants)OA: greenTopics (27)IDs (PubMed, OpenAlex)

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Authors (6)

Lindsay Morrison ORCID,Alexandre F. Gomes,Paul B. Savage ORCID,Amita R. Sahoo ORCID,Matthias Buck ORCID

Live enrichment

PubMed:40462934 OpenAlex:https://openalex.org/W4408495578

NIH

Grant: R01AG089561

NIH

Grant: R01EY029169

NCI-T32

Grant: T32CA094186

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/05/14/2025.03.13.643120.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.03.13.643120

repositoryhttps://doi.org/10.1101/2025.03.13.643120

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40462934

Fields of Study

Axon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology ResearchReceptor Mechanisms and SignalingBiologyMedicineComputer ScienceChemistry

Keywords

Allosteric regulationPlexinFunction (biology)GTPaseComputationTransmembrane proteinComputer scienceCell biologyComputational biologyReceptorBiologyGeneticsAlgorithmSemaphorinGTPasesMolecular dynamics simulationsPlexinsStructural biologyhydrogen-deuteriummass spectroscopy