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Glycoengineering of the hepatitis C virus E2 glycoprotein leads to improved biochemical properties and enhanced immunogenicity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.02.646860Source: DataRank Database

Glycoengineering of the hepatitis C virus E2 glycoprotein leads to improved biochemical properties and enhanced immunogenicity is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (26)IDs (PubMed, OpenAlex)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (20)

Kun Li ORCID,Austin W.T. Chiang ORCID,Michael P. Schwoerer ORCID,Sanne Schoffelen ORCID,Khadija Elkholy

Live enrichment

PubMed:40291659 OpenAlex:https://openalex.org/W4409218167

NIAID NIH HHS

Grant: R01 AI168048

NIGMS NIH HHS

Grant: T32 GM007388

NIGMS NIH HHS

Grant: R24 GM137782

NIGMS NIH HHS

Grant: R35 GM119850

NIAID NIH HHS

Grant: R01 AI107301

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/04/07/2025.04.02.646860.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.04.02.646860

repositoryhttps://doi.org/10.1101/2025.04.02.646860

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40291659

Fields of Study

Hepatitis C virus researchMonoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins Research

Keywords

ImmunogenicityGlycanEpitopeNeutralizationAntigenAntibodyAntigenicityVirologyGlycoproteinCD81BiologyChinese hamster ovary cellPotencyImmune systemEctodomainChemistryHepatitis C virusMolecular biologyVirusBiochemistryImmunologyReceptorIn vitro

Sustainable Development Goals

SDG 0: Good health and well-being