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An autism spectrum disorder mutation in Topoisomerase 3β causes accumulation of covalent mRNA intermediates by disrupting metal binding within the zinc finger domain

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.11.647616Source: DataRank Database

An autism spectrum disorder mutation in Topoisomerase 3β causes accumulation of covalent mRNA intermediates by disrupting metal binding within the zinc finger domain is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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0DataRank · unranked

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Open Access0 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)OA: greenTopics (18)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Durga Attili ORCID,Trevor van Eeuwen ORCID,Benjamin Pastore ORCID,Sarah E. Hoffmann-Weitsman,Nicholas C. Forsyth

Live enrichment

PubMed:40370956 OpenAlex:https://openalex.org/W4409377867

Grant: R35GM146924

Grant: R35GM142580

Grant: R01NS113943

Grant: R01NS097542

Grant: R56NS128110

Grant: MCB2420329

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/04/11/2025.04.11.647616.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.04.11.647616

repositoryhttps://doi.org/10.1101/2025.04.11.647616

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40370956

Fields of Study

Cancer therapeutics and mechanismsAcoustic Wave Resonator TechnologiesSemiconductor materials and devices

Keywords

Zinc fingerMessenger RNAMutationRING finger domainPoint mutationBiologyTopoisomeraseTranslation (biology)RNAGeneticsChemistryCell biologyDNAGeneTranscription factor

Sustainable Development Goals

SDG 0: Good health and well-being