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BRCA2 reversion mutation-independent resistance to PARP inhibition in prostate cancer through loss of function perturbations in the DNA pre-replication complex

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.20.649668Source: DataRank Database

BRCA2 reversion mutation-independent resistance to PARP inhibition in prostate cancer through loss of function perturbations in the DNA pre-replication complex is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (7 grants)OA: greenTopics (19)IDs (PubMed, OpenAlex)

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Authors (14)

Matteo Ferrari ORCID,Perianne Smith,Subhiksha Nandakumar ORCID,Zahra Khan,Serina B Young

Live enrichment

PubMed:26207759 OpenAlex:https://openalex.org/W4409758276

National Cancer Institute

Grant: CA008748

National Cancer Institute

Grant: NIH 1F32CA236126-01

National Cancer Institute

Grant: CA193837

National Cancer Institute

Grant: CA265768

National Cancer Institute

Grant: CA092629

Howard Hughes Medical Institute

Calico Life Sciences

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/04/24/2025.04.20.649668.full.pdf

GREENhttps://www.biorxiv.org/content/biorxiv/early/2025/04/24/2025.04.20.649668.full.pdf

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/04/24/2025.04.20.649668.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.04.20.649668

repositoryhttps://doi.org/10.1101/2025.04.20.649668

Fields of Study

PARP inhibition in cancer therapyBiologyMedicine

Keywords

ReversionProstate cancerMutationReplication (statistics)GeneticsPoly ADP ribose polymeraseCancer researchFunction (biology)BiologyDNA replicationDNACancerGenePhenotypeVirologyPolymerase