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Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza hemagglutinin

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.24.655919Source: DataRank Database

Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza hemagglutinin is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

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Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)OA: greenTopics (21)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Caroline Kikawa ORCID,Bernadeta Dadonaite ORCID,Andrea N. Loes ORCID,Janet A. Englund ORCID,Jesse D. Bloom ORCID

Live enrichment

PubMed:40475658 OpenAlex:https://openalex.org/W4410717046

Grant: T32 GM007270

Grant: DGE-2140004

Grant: R01 AI165821

Grant: 75N93021C00015

National Institutes of Health

Grant: S10-OD-020069

National Institutes of Health

Grant: S10-OD-028685

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/05/24/2025.05.24.655919.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.05.24.655919

repositoryhttps://doi.org/10.1101/2025.05.24.655919

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40475658

Fields of Study

Influenza Virus Research StudiesProtein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Keywords

EpistasisAntigenic driftHemagglutinin (influenza)BiologyMutationGeneticsMutagenesisInfluenza A virusPopulationAntigenVirologyAntigenic variationAntigenic shiftH5N1 genetic structureFunction (biology)VirusGeneCoronavirus disease 2019 (COVID-19)

Sustainable Development Goals

SDG 0: Good health and well-being