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Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia via a cytotoxic integrated stress response

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.06.657881Source: DataRank Database

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia via a cytotoxic integrated stress response is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)OA: greenTopics (15)IDs (PubMed, OpenAlex)

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Open Access

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Reusable (0/3)

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Authors (23)

Su‐Fern Tan ORCID,Jeremy J.P. Shaw ORCID,Maansi Taori,Tess M. Deddens,Giovana da Costa Venancio

Live enrichment

PubMed:40501740 OpenAlex:https://openalex.org/W4411118563

Veteran’s Administration VA Merit Review

Grant: I BX001792

Research Career Scientist Award

Grant: IK6BX004603

NIH/NCI

Grant: P01 CA171983

NIH/NCI

Grant: P30 CA044579

NIH/NCI

Grant: F31 CA271809

NIH/NCI

Grant: F99 CA284252

NIH/NIAID

Grant: R01 AI139072

UVA

Grant: Robert R. Wagner Fellowship

greenLicense: https://www.biorxiv.org/about/FAQ#license

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/06/07/2025.06.06.657881.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.06.06.657881

repositoryhttps://doi.org/10.1101/2025.06.06.657881

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40501740

Fields of Study

Acute Myeloid Leukemia ResearchHistone Deacetylase Inhibitors ResearchUbiquitin and proteasome pathways

Keywords

VenetoclaxMyeloid leukemiaCytotoxic T cellCancer researchLeukemiaPharmacologyChemistryMedicineImmunologyBiochemistryIn vitroChronic lymphocytic leukemia