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Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.23.661098Source: DataRank Database

Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (16)IDs (PubMed, OpenAlex)SDGs (1)

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Reusable (0/3)

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Authors (11)

Hailey Axemaker,Kristin Calar,Oduduabasi Isaiah,Jared Wollman,Somshuvra Bhattacharya ORCID

Live enrichment

PubMed:40667179 OpenAlex:https://openalex.org/W4411935610

National Institutes of Health

Grant: R21CA259158

National Institutes of Health

Grant: R37CA291976

National Institutes of Health

Grant: P30GM145398

National Institutes of Health

Grant: P30GM154633

Grant: RSG-23-1149466-01-CDP

greenLicense: cc-by

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12262685

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.06.23.661098

repositoryhttps://doi.org/10.1101/2025.06.23.661098

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40667179

Fields of Study

Immune cells in cancerCancer Cells and MetastasisSingle-cell and spatial transcriptomics

Keywords

Immune systemStromal cellExtracellular matrixTumor microenvironmentCancer researchInfiltration (HVAC)Hypoxia (environmental)BiologyCell biologyImmunologyChemistryMaterials scienceOxygen

Sustainable Development Goals

SDG 0: Good health and well-being