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LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.03.663042Source: DataRank Database

LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)OA: greenTopics (15)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Gisele Nishiguchi ORCID,Satoshi Yoshimura ORCID,Marisa Actis,Justin T. Seffernick,Jamie Jarusiewicz ORCID

Live enrichment

PubMed:40672235 OpenAlex:https://openalex.org/W4412086333

National Institutes of Health

Grant: P30 CA021765

National Institutes of Health

Grant: R01CA264837

greenLicense: https://www.biorxiv.org/about/FAQ#license

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/07/07/2025.07.03.663042.full.pdf

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/07/07/2025.07.03.663042.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.07.03.663042

repositoryhttps://doi.org/10.1101/2025.07.03.663042

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40672235

Fields of Study

Protein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsPeptidase Inhibition and Analysis

Keywords

Cancer researchContext (archaeology)KinaseCancer cellChemistryCancerDrug resistanceTargeted therapyDrug discoveryBiologyBiochemistryGenetics

Sustainable Development Goals

SDG 0: Good health and well-being