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Lower Hippocampal Volume Partly Mediates the Association Between rs6859 in the NECTIN2 Gene and Alzheimer’s Disease: New Findings from Causal Mediation Analysis of ADNI Data

medRxiv(2025)10.1101/2025.09.02.25334930Source: DataRank Database

Lower Hippocampal Volume Partly Mediates the Association Between rs6859 in the NECTIN2 Gene and Alzheimer’s Disease: New Findings from Causal Mediation Analysis of ADNI Data is a research paper published in medRxiv (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (3 grants)OA: greenTopics (21)IDs (PubMed, OpenAlex)Annotations (1)

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Authors (6)

Konstantin G. Arbeev ORCID,Olivia Bagley,Anatoliy I. Yashin ORCID,Svetlana Ukraintseva ORCID,the Alzheimer’s Disease Neuroimaging Initiative

Live enrichment

PubMed:40950481 OpenAlex:https://openalex.org/W4413975840

NIA NIH HHS

Grant: R01 AG070487

NIA NIH HHS

Grant: R01 AG076019

NIA NIH HHS

Grant: U01 AG024904

greenLicense: cc-by-nd

repositoryhttps://www.medrxiv.org/content/medrxiv/early/2025/09/04/2025.09.02.25334930.full.pdf

GREENhttps://www.medrxiv.org/content/medrxiv/early/2025/09/04/2025.09.02.25334930.full.pdf

repositoryhttps://www.medrxiv.org/content/medrxiv/early/2025/09/04/2025.09.02.25334930.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.09.02.25334930

repositoryhttps://doi.org/10.1101/2025.09.02.25334930

Fields of Study

Nuclear Receptors and SignalingGenetic Associations and EpidemiologyGenomics and Rare DiseasesMedicineBiology

Keywords

MediationAssociation (psychology)Hippocampal formationDiseaseNeurosciencePsychologyMedicineInternal medicinePolitical sciencePsychotherapistAlzheimer’s diseaseCausal Mediation AnalysisHippocampal volumeInfectionsNECTIN2rs6859