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Unmixing of Imaging Mass Spectrometry Measurements Using Microscopy-Informed Constraints

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.29.685281Source: DataRank Database

Unmixing of Imaging Mass Spectrometry Measurements Using Microscopy-Informed Constraints is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (8 grants)OA: greenTopics (23)IDs (PubMed, OpenAlex)

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Authors (7)

Nathan Heath Patterson ORCID,Lukasz G. Migas ORCID,Allison B. Esselman ORCID,Felipe Moser ORCID,Jeffrey M. Spraggins ORCID

Live enrichment

PubMed:41279206 OpenAlex:https://openalex.org/W4415714061

NIDDK NIH HHS

Grant: U54 DK134302

NIA NIH HHS

Grant: R01 AG078803

NIDDK NIH HHS

Grant: U54 DK120058

NCI NIH HHS

Grant: U01 CA294527

NIAID NIH HHS

Grant: R01 AI145992

NIAID NIH HHS

Grant: R01 AI138581

NEI NIH HHS

Grant: U54 EY032442

NIDDK NIH HHS

Grant: U01 DK133766

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/10/30/2025.10.29.685281.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.10.29.685281

repositoryhttps://doi.org/10.1101/2025.10.29.685281

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41279206

Fields of Study

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and ApplicationsIon-surface interactions and analysisMedicineBiologyChemistryComputer ScienceMaterials Science

Keywords

Overdetermined systemUnderdetermined systemThresholdingInverse problemMixing (physics)Basis (linear algebra)InverseMultispectral imageImaging Mass SpectrometryIn-Situ Single CellLarge ScaleMatrix CompletionNon-NegativitySparsityUnmixing