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Key residues in SARS-CoV-2 NSP3 hyper variable region are necessary to modulate early stress granule activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.22.689758Source: DataRank Database

Key residues in SARS-CoV-2 NSP3 hyper variable region are necessary to modulate early stress granule activity is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)OA: greenTopics (32)IDs (PubMed, OpenAlex)

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Authors (14)

Kumari G. Lokugamage,Dimitriya H. Garvanska,Leah K. Estes,Yani P. Ahearn,Alyssa M. McLeland

Live enrichment

PubMed:41394631 OpenAlex:https://openalex.org/W4416716155

Grant: R01-AI153602

Grant: R21-AI145400

Grant: U19-AI171413

NIAID NIH HHS

Grant: T32AI007526

Grant: Investigator in Pathogenesis

Novo Nordisk Foundation Center for Protein Research

Grant: NNF14CC0001

Novo Nordisk Foundation

Grant: unidentified

unidentified

NIAID NIH HHS

Grant: R01 AI153602

NIAID NIH HHS

Grant: R21 AI145400

NIAID NIH HHS

Grant: U19 AI171413

greenLicense: cc-by-nc

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/11/24/2025.11.22.689758.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2025.11.22.689758

repositoryhttps://doi.org/10.1101/2025.11.22.689758

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41394631

Fields of Study

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesViral Infections and Immunology Research0301 basic medicine03 medical and health sciences

Keywords

Granule (geology)Stress granuleViral replicationMutantTyrosinePhenylalaninePlasma protein bindingstress granulesSARS-CoV-2coronavirusNSP3nucleocapsidCOVID-19RNA-Binding ProteinsFXR1Viral Nonstructural ProteinsVirus ReplicationArticleVirus-Cell InteractionsMiceRNA Recognition Motif ProteinsChlorocebus aethiopsMutationHumansAnimalsVero CellsProtein Binding