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ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs

Genes & Development(2020)10.1101/gad.335836.119Source: DataRank Database

ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs is a research paper published in Genes & Development (2020). On theSindex it has a DataRank of 0.665. It has been cited 83 times.

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0.665DataRank · unranked

Scored on demand from live citation data

Open Access83 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)OA: goldTopics (48)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.665

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (8)

Tristan H. Coady,Lei Lü ORCID,Dinghai Zheng ORCID,Isabel Alland,Bin Tian ORCID

Live enrichment

PubMed:32381627 OpenAlex:https://openalex.org/W3022460653

National Institutes of Health

Grant: R35 GM118136

National Institutes of Health

Grant: Government Scholarship to Study Abroad

NIH

Grant: GM084089

NIH

Grant: GM129069

National Institutes of Health

Grant: 5R35GM118136-02

Regulation of mRNA processing: Mechanisms and consequences

National Institutes of Health

Grant: 5R01GM129069-04

Regulation and Functions of 3'UTRs in Cellular Stress

National Institutes of Health

Grant: 3R01GM084089-12S2

Regulation of Alternatiive Cleavage and Polyadenylation

goldLicense: cc-by-nc

journalhttp://genesdev.cshlp.org/content/34/11-12/785.full.pdf

publisherhttp://genesdev.cshlp.org/content/34/11-12/785.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.335836.119

journalhttps://doi.org/10.1101/gad.335836.119

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32381627

Fields of Study

Amyotrophic Lateral Sclerosis ResearchMitochondrial Function and PathologyGenetic Neurodegenerative Diseases0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Amyotrophic Lateral SclerosisCell LineCells, CulturedElectron TransportGene Expression RegulationHumansMitochondriaMutationProtein BindingRNA, MessengerCell RespirationRNA-Binding Protein FUSGenome, MitochondrialProtein Aggregation, Pathological

Keywords

BiologyMitochondrionRespiratory chainMitochondrial DNAMutantCell biologyMutationMitochondrial respiratory chainGeneMolecular biologyRNADNAJA3Geneticsmitochondrial fusionAmyotrophic Lateral SclerosisCell RespirationProtein Aggregation, PathologicalCell LineMitochondriaElectron TransportGene Expression RegulationGenome, MitochondrialHumansRNA-Binding Protein FUSRNA, MessengerCells, CulturedResearch PaperProtein Binding