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Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription

Genes & Development(2020)10.1101/gad.341545.120Source: DataRank Database

Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription is a research paper published in Genes & Development (2020). On theSindex it has a DataRank of 0. It has been cited 88 times.

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Enrichment:Funding (14 grants)OA: goldTopics (44)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC, OpenAlex)Annotations (4)

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Authors (29)

Zachary C. Poss,Benjamin Erickson ORCID,Zachary L. Maas ORCID,Christopher C. Ebmeier ORCID,Jared L. Johnson ORCID

Live enrichment

PubMed:33060135 PMC:PMC7608751 OpenAlex:https://openalex.org/W3093156639

National Institutes of Health

Grant: OD12300

NIH

Grant: GM118051

NIH

Grant: GM110064

NIH

Grant: T32GM065103

National Cancer Institute

Grant: R21CA205912

National Cancer Institute

Grant: F31CA250432

German Research Foundation

Grant: DE 3069/1-1

German Research Foundation

Grant: GE 976/9-2

National Science Foundation

Grant: MCB1818147

National Science Foundation

Grant: ABI1759949

National Science Foundation

Grant: MCB1903300

NIH HHS

Grant: S10 OD012300

NIGMS NIH HHS

Grant: R35 GM118051

NIGMS NIH HHS

Grant: R01 GM110064

goldLicense: cc-by-nc

journalhttp://genesdev.cshlp.org/content/34/21-22/1452.full.pdf

publisherhttp://genesdev.cshlp.org/content/34/21-22/1452.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.341545.120

journalhttps://doi.org/10.1101/gad.341545.120

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33060135

Fields of Study

RNA Research and SplicingRNA modifications and cancerGenomics and Chromatin Dynamics

MeSH Terms

Cyclin-Dependent Kinase-Activating KinaseCell SurvivalEnzyme ActivationHumansModels, BiologicalTranscription, GeneticAlternative SplicingCyclin-Dependent KinasesHL-60 CellsTranscription Factor TFIIH

Keywords

Cyclin-dependent kinase 7Transcription factor II HBiologyRNA polymerase IITranscription (linguistics)Cyclin-dependent kinaseRNA polymerase II holoenzymeCell biologyKinaseGeneral transcription factorRNA splicingMolecular biologyGeneticsPromoterRNAProtein kinase ARNA polymeraseGeneGene expressionCyclin-dependent kinase 2Cell cycleTranscriptionSplicingCDK9Kinase InhibitorTfiihCdk12Cdk13Sf3b1Cdk7Silac-ms

Additional file 4 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803060.v1figshare

Additional file 4 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803060figshare

Additional file 3 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803057figshare

Additional file 1 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803051.v1figshare

Additional file 1 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803051figshare

Additional file 2 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803054.v1figshare

Additional file 2 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803054figshare

Additional file 3 of Novel covalent CDK7 inhibitor potently induces apoptosis in acute myeloid leukemia and synergizes with Venetoclax

10.6084/m9.figshare.23803057.v1figshare

Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription

FAIR Checklist

Authors (29)

Funding (14 grants)

Open Access

Topics

Linked Datasets (8)

Annotations (Europe PMC)