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A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

Genes & Development(2020)10.1101/gad.344556.120Source: DataRank Database

A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21 is a research paper published in Genes & Development (2020). On theSindex it has a DataRank of 0. It has been cited 43 times.

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Open Access43 citations

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Enrichment:Funding (22 grants)OA: goldTopics (79)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Authors (7)

Rachel J. Perry ORCID,João Paulo Camporez ORCID,Philipp E. Scherer ORCID,Gerald I. Shulman ORCID,Guangping Gao ORCID

Live enrichment

PubMed:33334822 PMC:PMC7778269 OpenAlex:https://openalex.org/W3114921148

American Heart Association

Grant: 19CDA34660270

Sao Paulo Research Foundation

Grant: 2018/04956-5

National Institutes of Health

Grant: R01 DK107220

National Institutes of Health

Grant: R01 DK112698

National Institutes of Health

Grant: R00 CA215315

National Institutes of Health

Grant: R01 DK55758

National Institutes of Health

Grant: P01 AG051459

National Institutes of Health

Grant: R01 DK116774

National Institutes of Health

Grant: R01 DK114793

National Institutes of Health

Grant: P30 DK045735

NCATS NIH HHS

Grant: UL1 TR001863

NIDDK NIH HHS

Grant: R01 DK121545

NIDDK NIH HHS

Grant: R01 DK055758

NIDDK NIH HHS

Grant: P30 DK034989

National Institutes of Health

Grant: 5R01DK114793-04

Microbiome origins and insulin regulatory responses of the short chain fatty acid acetate

National Institutes of Health

Grant: 1R01DK055758-01A1

ACRP, A PROTEIN SECRETED FROM ADIPOSE TISSUE

National Institutes of Health

Grant: 5R01DK107220-07

Metabolic Stress Signaling

National Institutes of Health

Grant: 5P01AG051459-04

Impact of FGF21 on healthspan and lifespan

National Institutes of Health

Grant: 5R01DK112698-07

Adipose Tissue Metabolic Stress Responses

National Institutes of Health

Grant: 5P30DK045735-28

Yale Diabetes Research Center

National Institutes of Health

Grant: 4R00CA215315-03

Regulation of tumor growth and metabolism by hyperinsulinemia

National Institutes of Health

Grant: 5R01DK116774-02

Glucagon Regulation of Hepatic Mitochondrial Activity and Glucose Metabolism by InsP3R-1

goldLicense: cc-by-nc

journalhttp://genesdev.cshlp.org/content/35/1-2/133.full.pdf

publisherhttp://genesdev.cshlp.org/content/35/1-2/133.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.344556.120

journalhttps://doi.org/10.1101/gad.344556.120

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33334822

Fields of Study

Fibroblast Growth Factor ResearchKruppel-like factors researchEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciencesAdipocytesAdiponectinAdipose TissueAnimalsAutocrine CommunicationEndocrine SystemEnergy MetabolismFeedback, PhysiologicalFibroblast Growth FactorsGene Expression RegulationHepatocytesInsulin ResistanceLiverMAP Kinase Kinase 4MAP Kinase Signaling SystemMiceSignal Transduction

MeSH Terms

Adipose TissueAnimalsEndocrine SystemEnergy MetabolismFibroblast Growth FactorsGene Expression RegulationInsulin ResistanceLiverSignal TransductionAdipocytesAutocrine CommunicationMAP Kinase Signaling SystemHepatocytesFeedback, PhysiologicalMAP Kinase Kinase 4MiceAdiponectin

Keywords

BiologyAdipose tissueFGF21Cell biologySignal transductionComputational biologyBioinformaticsEndocrinologyGeneticsFibroblast growth factorReceptorEndocrineAutocrineJNKOrgan Cross-talk570Biochemical Phenomenaand Hormone AntagonistsMAP Kinase Kinase 4MAP Kinase Signaling System610Endocrine SystemMiceAdipocytesAnimalsand NutritionFeedback, PhysiologicalHormonesCellular and Molecular PhysiologyFibroblast Growth FactorsAutocrine CommunicationMetabolismGene Expression RegulationLiverHepatocytesHormone SubstitutesAdiponectinInsulin ResistanceEnergy MetabolismResearch Paper

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China

10.6084/m9.figshare.15071210.v1figshare

Additional file 1 of FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China

10.6084/m9.figshare.15071210figshare