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miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts

Genes & Development(2021)10.1101/gad.347344.120Source: DataRank Database

miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts is a research paper published in Genes & Development (2021). On theSindex it has a DataRank of 0. It has been cited 72 times.

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Enrichment:Funding (22 grants)OA: goldTopics (79)Linked Datasets (4)DataCite Reuse (4)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

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Authors (17)

Chen-Hua Chuang ORCID,Haydn M. Prosser ORCID,César Seigi Fuziwara ORCID,Claudia Chan,Neil Sahasrabudhe

Live enrichment

PubMed:34301766 PMC:PMC8336896 OpenAlex:https://openalex.org/W3186531850

National Institutes of Health

Grant: R01CA139067

National Institutes of Health

Grant: 1R21OD027053

NIH

Grant: R01-CA175336

NIH

Grant: R01-CA204620

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo

Grant: FAPESP:2017:01829-0

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo

Grant: 2019/17282-5

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo

Grant: 5U01CA217882

W.M. Keck Foundation

Grant: 81572269

NIH HHS

Grant: R21 OD027053

NCI NIH HHS

Grant: U01 CA217882

NCI NIH HHS

Grant: R01 CA175336

NCI NIH HHS

Grant: R01 CA204620

National Institutes of Health

Grant: 1R01CA175336-01

Molecular Dissection of Lung Cancer Progression and Metastasis

National Institutes of Health

Grant: 1U01CA217882-01

The Cancer Target Discovery and Development Network at UCSF

National Institutes of Health

Grant: 1R21OD027053-01

Rapid Fluorescent Tagging of Endogenous Proteins in Mouse Models

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1R01CA139067-01

Functions of mir-34 microRNAs in the p53 tumor suppressor pathway

National Institutes of Health

Grant: 5R01CA204620-05

Molecular Dissection of an Arntl2 induced pro-metastatic secretome

Bakar Fellow

National Natural Science Foundation of China

American Lung Association Fellowship

Howard Hughes Medical Institute

goldLicense: cc-by-nc

journalhttp://genesdev.cshlp.org/content/35/15-16/1109.full.pdf

publisherhttp://genesdev.cshlp.org/content/35/15-16/1109.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.347344.120

journalhttps://doi.org/10.1101/gad.347344.120

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34301766

Fields of Study

MicroRNA in disease regulationCancer-related molecular mechanisms researchCircular RNAs in diseases0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsCancer-Associated FibroblastsCell Line, TumorCell ProliferationFibroblastsGene Expression Regulation, NeoplasticHumansLung NeoplasmsMiceMicroRNAsNeoplasm Metastasis

MeSH Terms

Cancer-Associated FibroblastsAnimalsFibroblastsHumansLung NeoplasmsNeoplasm MetastasisGene Expression Regulation, NeoplasticMicroRNAsCell Line, TumorCell ProliferationMice

Keywords

BiologyMetastasisLung cancerCancer researchAdenocarcinomaCancerNotch signaling pathwayCancer-Associated FibroblastsCancer cellmicroRNAPathologySignal transductionMedicineCell biologyGenemiRNAMicroenvironmentMir-200Jag1Mir-200cMir-141Jag2Biomedical and clinical sciencesLung NeoplasmsOncology and Carcinogenesis610Medical and Health SciencesCell LineMiceRare DiseasesCell Line, Tumor617Genetics2.1 Biological and endogenous factorsPsychologyAnimalsHumansNeoplasm MetastasisLungCell ProliferationNeoplasticTumorPsychology and Cognitive SciencesBiological SciencesFibroblastsGene Expression Regulation, NeoplasticMicroRNAsGene Expression RegulationWomen's HealthDevelopmental BiologyResearch Paper

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin

10.6084/m9.figshare.20408788.v1figshare

Additional file 1 of The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin

10.6084/m9.figshare.20408788figshare

Additional file 2 of The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin

10.6084/m9.figshare.20408791.v1figshare

Additional file 2 of The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin

10.6084/m9.figshare.20408791figshare

miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts

FAIR Checklist

Authors (17)

Funding (22 grants)

Open Access

Topics

Linked Datasets (4)

Annotations (Europe PMC)