Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

Genes & Development(2023)10.1101/gad.350569.123Source: DataRank Database

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain is a research paper published in Genes & Development (2023). On theSindex it has a DataRank of 0. It has been cited 17 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access17 citations

Download PDF

Cite:

Linked data & code

geo

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)OA: goldTopics (34)Linked Datasets (4)DataCite Reuse (4)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (14)

Joshua A. Levine ORCID,Angela J. Churchill,Bryce Hopwood,Cailin Deiter ORCID,Michelle A. Guney

Live enrichment

PubMed:37364986 PMC:PMC10393193 OpenAlex:https://openalex.org/W4382055135

National Institutes of Health

Grant: F31 NS092246

National Institutes of Health

Grant: T32 GM007088

National Institutes of Health

Grant: R01 DK082590

National Institutes of Health

Grant: R01 DK118155

National Institutes of Health

Grant: U01 DK127505

National Institutes of Health

Grant: P30 DK057516

National Institutes of Health

Grant: R01 NS109217

National Institutes of Health

Grant: R21 NS092043

NYSTEM

Grant: C028112

NIGMS NIH HHS

Grant: T32 GM087237

NINDS NIH HHS

Grant: R01 NS116141

National Institutes of Health

Grant: 5R01NS109217-03

Distal enhancers controlling motor neuron gene expression program

National Institutes of Health

Grant: 5R01DK082590-17

Regulation of pancreatic islet cell fate

National Institutes of Health

Grant: 1F31NS092246-01A1

Regulation of motor neuron enhancers by the transcription factor Nkx2.2

National Institutes of Health

Grant: 5R01DK118155-04

Intersection of signaling pathways and transcription factors regulating islet development

National Institutes of Health

Grant: 5U01DK127505-02

Alternative RNA splicing events contribute to the onset of islet dysfunction in T1D

National Institutes of Health

Grant: 5P30DK057516-04

UCHSC DIABETES ENDOCRINOLOGY RESEARCH CENTER

National Institutes of Health

Grant: 2T32GM007088-17

HUMAN GENETICS AND DEVELOPMENT

National Institutes of Health

Grant: 1R21NS092043-01

Stable silencing of spinal motor neuron enhancers by transiently expressed Nkx2.2

National Science Foundation

goldLicense: cc-by

journalhttp://genesdev.cshlp.org/content/early/2023/06/26/gad.350569.123.full.pdf

publisherhttp://genesdev.cshlp.org/content/early/2023/06/26/gad.350569.123.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.350569.123

journalhttps://doi.org/10.1101/gad.350569.123

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37364986

Fields of Study

Pancreatic function and diabetesGenetics and Neurodevelopmental Disorders0301 basic medicine03 medical and health sciences

MeSH Terms

Homeobox Protein Nkx-2.2Cell DifferentiationTranscription FactorsHomeodomain ProteinsZebrafish ProteinsInsulin-Secreting Cells

Keywords

BiologyTranscription factorChromatinCell biologyCell fate determinationRegulation of gene expressionCell typeCellTranscriptional regulationPsychological repressionGeneGene expressionGeneticsSpinal cordNkx2.2β cellspancreatic isletHomeodomain ProteinsHomeobox Protein Nkx-2.2Insulin-Secreting CellsCell DifferentiationZebrafish ProteinsResearch PapersTranscription Factors

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of Developmentally dynamic changes in DNA methylation in the human pancreas

10.6084/m9.figshare.25963174.v1figshare

Additional file 1 of Developmentally dynamic changes in DNA methylation in the human pancreas

10.6084/m9.figshare.25963174figshare

Additional file 2 of Developmentally dynamic changes in DNA methylation in the human pancreas

10.6084/m9.figshare.25963269figshare

Additional file 2 of Developmentally dynamic changes in DNA methylation in the human pancreas

10.6084/m9.figshare.25963269.v1figshare

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

FAIR Checklist

Authors (14)

Funding (20 grants)

Open Access

Topics

Linked Datasets (4)

Annotations (Europe PMC)