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LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities

Genes & Development(2023)10.1101/gad.351051.123Source: DataRank Database

LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities is a research paper published in Genes & Development (2023). On theSindex it has a DataRank of 0. It has been cited 104 times.

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Open Access104 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)OA: goldTopics (39)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Kathleen H. Burns ORCID,Carlos Mendez‐Dorantes ORCID

Live enrichment

PubMed:38092519 PMC:PMC10760644 OpenAlex:https://openalex.org/W4389660930

National Institutes of Health

Grant: R01CA240816

National Institutes of Health

Grant: R01CA276112

National Institutes of Health

Grant: UG3NS132127

Dana-Farber Cancer Institute

Grant: Innovations Research Fund

National Institutes of Health

Grant: 1R01CA276112-01A1

Consequences of retrotransposition on genome integrity

National Institutes of Health

Grant: 5UG3NS132127-02

Single Molecule Detection of L1 Insertions and Intermediates

National Institutes of Health

Grant: 1R01CA240816-01A1

Characterizing the LINE-1 Retrotransposition-Replication Conflict

Jane Coffin Childs Memorial Fund for Medical Research

goldLicense: cc-by-nc

journalhttp://genesdev.cshlp.org/content/early/2023/12/13/gad.351051.123.full.pdf

publisherhttp://genesdev.cshlp.org/content/early/2023/12/13/gad.351051.123.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.351051.123

journalhttps://doi.org/10.1101/gad.351051.123

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38092519

Fields of Study

Chromosomal and Genetic VariationsCRISPR and Genetic EngineeringPlant Virus Research Studies03 medical and health sciences0302 clinical medicineHumansLong Interspersed Nucleotide ElementsNeoplasmsRNAProteinsEpigenesis, Genetic

MeSH Terms

HumansNeoplasmsProteinsRNALong Interspersed Nucleotide ElementsEpigenesis, Genetic

Keywords

RetrotransposonBiologyTransposable elementGeneticsEpigeneticsGenomeRNA interferenceGene silencingEpigenomeRNADNA methylationComputational biologyGeneGene expressionGenome InstabilityLine-1 RetrotransposonsLong Interspersed Nucleotide ElementsNeoplasmsHumansProteinsReviewEpigenesis, Genetic

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being