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Hyd/UBR5 defines a tumor suppressor pathway that links Polycomb repressive complex to regulated protein degradation in tissue growth control and tumorigenesis

Genes & Development(2024)10.1101/gad.351856.124Source: DataRank Database

Hyd/UBR5 defines a tumor suppressor pathway that links Polycomb repressive complex to regulated protein degradation in tissue growth control and tumorigenesis is a research paper published in Genes & Development (2024). On theSindex it has a DataRank of 0. It has been cited 5 times.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (21 grants)OA: goldTopics (59)IDs (PubMed, PMC, OpenAlex)SDGs (1)

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Authors (9)

Huiyan Lei,Hua Deng ORCID,Su Deng ORCID,Carla R. Tirado ORCID,Meiling Wang ORCID

Live enrichment

PubMed:39137945 PMC:PMC11368183 OpenAlex:https://openalex.org/W4401539263

National Institutes of Health

Grant: EY015708

National Institutes of Health

Grant: R00CA218885

National Institutes of Health

Grant: R37CA258730

National Institutes of Health

Grant: 1F31CA261019-01A1

Dissecting the role of UBE2J1 in prostate cancer

National Institutes of Health

Grant: T32C124334

Department of Defense

Grant: W81XWH-18-1-0411

Department of Defense

Grant: W81XWH21-1-0520

Cancer Prevention Research Institute

Grant: RR170050

Cancer Prevention Research Institute

Grant: RP220473

NEI NIH HHS

Grant: R01 EY015708

NIH HHS

Grant: P40 OD010949

NCI NIH HHS

Grant: R01 CA292949

NCI NIH HHS

Grant: F31 CA261019

NIH HHS

Grant: P40 OD018537

National Institutes of Health

Grant: 7R37CA258730-05

Elucidating the Molecular Role of SYNCRIP in Prostate Cancer and AR Targeted Therapy Resistance

National Institutes of Health

Grant: 5T32CA124334-04

Cancer Biology Training Grant

National Institutes of Health

Grant: 3P40OD018537-04S1

Bloomington Drosophila Stock Center at Indiana University

National Institutes of Health

Grant: 5R01EY015708-17

Control of Cell Number in Developing Retina

National Institutes of Health

Grant: 5R00CA218885-03

Overcome the lineage plasticity conferred targeted therapy resistance in advanced prostate cancer

National Institutes of Health

Grant: 5P40OD010949-14

Drosophila Genomics Resource Center

University of Texas Southwestern Kirkpatrick

goldLicense: cc-by

journalhttps://doi.org/10.1101/gad.351856.124

publisherhttps://doi.org/10.1101/gad.351856.124

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.351856.124

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39137945

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11368183

Fields of Study

Epigenetics and DNA Methylation0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsUbiquitin-Protein LigasesDrosophila ProteinsCarcinogenesisProteolysisHumansTumor Suppressor ProteinsDrosophila melanogasterGenes, Tumor SuppressorUbiquitinationPolycomb-Group ProteinsPolycomb Repressive Complex 1

MeSH Terms

AnimalsDrosophila melanogasterHumansGenes, Tumor SuppressorTumor Suppressor ProteinsDrosophila ProteinsUbiquitin-Protein LigasesUbiquitinationProteolysisPolycomb-Group ProteinsPolycomb Repressive Complex 1Carcinogenesis

Keywords

BiologyCarcinogenesisSuppressorCell biologyCancer researchPolycomb-group proteinsGeneticsRepressorTranscription factorGeneTumor suppressorLinesprostate cancerE3 ubiquitin ligasePolycomb Repressive ComplexUbr5BowlLins1Hyperplastic DiscOsr1/2Polycomb Repressive Complex 1Ubiquitin-Protein LigasesTumor Suppressor ProteinsUbiquitinationResearch PapersDrosophila melanogasterProteolysisAnimalsDrosophila ProteinsHumansGenes, Tumor Suppressor

Sustainable Development Goals

SDG 0: Good health and well-being