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UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast

Genes & Development(2025)10.1101/gad.352490.124Source: DataRank Database

UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast is a research paper published in Genes & Development (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (7 grants)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)

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Authors (7)

Allison J. Kim,Yanzhe Ma,Thiago P. Fernandes,Charles Boone ORCID,Marko Jovanović ORCID

Live enrichment

PubMed:40846641 PMC:PMC12667388 OpenAlex:https://openalex.org/W4413419092

National Institutes of Health

Grant: R01AG071869

National Institutes of Health

Grant: T32GM008295

National Institutes of Health

Grant: T32GM148378

NIGMS NIH HHS

Grant: R35 GM134886

National Institutes of Health

Grant: 5T32GM148378-02

Molecular Biology Across Scales Training Program

National Institutes of Health

Grant: 5T32GM008295-26

Molecular Biophysics Training Grant

National Institutes of Health

Grant: 5R01AG071869-05

Defining the programmed proteome rejuvenation underlying gametogenesis

goldLicense: cc-by-nc

journalhttp://genesdev.cshlp.org/content/early/2025/08/22/gad.352490.124.full.pdf

publisherhttp://genesdev.cshlp.org/content/early/2025/08/22/gad.352490.124.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.352490.124

journalhttps://doi.org/10.1101/gad.352490.124

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40846641

Fields of Study

Endoplasmic Reticulum Stress and DiseaseFungal and yeast genetics researchBiofuel production and bioconversion0301 basic medicine03 medical and health sciencesUnfolded Protein ResponseAneuploidyProteostasisSaccharomyces cerevisiaeEndoplasmic ReticulumEndoplasmic Reticulum StressSaccharomyces cerevisiae ProteinsGene Expression Regulation, FungalProtein Folding

MeSH Terms

ProteostasisAneuploidyEndoplasmic ReticulumSaccharomyces cerevisiaeGene Expression Regulation, FungalProtein FoldingSaccharomyces cerevisiae ProteinsUnfolded Protein ResponseEndoplasmic Reticulum Stress

Keywords

ProteostasisBiologyUnfolded protein responseAneuploidyCell biologyEndoplasmic reticulumChromosome instabilityMitosisGeneticsGeneChromosomeYeastUprProtein FoldingSaccharomyces cerevisiae ProteinsGene Expression Regulation, FungalSaccharomyces cerevisiaeEndoplasmic Reticulum StressResearch Paper