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A distal enhancer with ETV4 binding is critical for UCP1 expression and thermogenesis in brown fat

Genes & Development(2025)10.1101/gad.352748.125Source: DataRank Database

A distal enhancer with ETV4 binding is critical for UCP1 expression and thermogenesis in brown fat is a research paper published in Genes & Development (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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Enrichment:Funding (2 grants)OA: goldTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Nicholas D Holloway ORCID,Alexander Tran ORCID,Frances Lin ORCID,Jennie Dinh ORCID,Caleb Yang

Live enrichment

PubMed:40324882 PMC:PMC12211996 OpenAlex:https://openalex.org/W4410084820

National Institutes of Health

Grant: 1R01DK140318-01

NIDDK NIH HHS

Grant: R01 DK140318

goldLicense: cc-by

journalhttp://genesdev.cshlp.org/content/early/2025/05/02/gad.352748.125.full.pdf

publisherhttp://genesdev.cshlp.org/content/early/2025/05/02/gad.352748.125.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.352748.125

journalhttps://doi.org/10.1101/gad.352748.125

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40324882

Fields of Study

Adipose Tissue and MetabolismMuscle metabolism and nutritionLipid metabolism and biosynthesisAnimalsThermogenesisAdipose Tissue, BrownUncoupling Protein 1MiceEnhancer Elements, GeneticObesityProtein BindingProto-Oncogene Proteins c-etsGene Expression RegulationMice, Inbred C57BLAdenovirus E1A ProteinsMaleInsulin Resistance

MeSH Terms

Uncoupling Protein 1AnimalsAdipose Tissue, BrownEnhancer Elements, GeneticGene Expression RegulationInsulin ResistanceMaleMice, Inbred C57BLObesityProtein BindingAdenovirus E1A ProteinsThermogenesisProto-Oncogene Proteins c-etsMice

Keywords

BiologyThermogenesisEnhancerThermogeninBrown adipose tissueChromatinCell biologyGene expressionAdipose tissueGeneGeneticsEndocrinologyTranscription factorBrown FatUcp1

A distal enhancer with ETV4 binding is critical for UCP1 expression and thermogenesis in brown fat

FAIR Checklist

Authors (9)

Funding (2 grants)

Open Access

Topics

Annotations (Europe PMC)