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A genome-wide, CRISPR-based screen reveals new requirements for translation initiation and ubiquitination in driving adipogenic fate change

Genes & Development(2025)10.1101/gad.352779.125Source: DataRank Database

A genome-wide, CRISPR-based screen reveals new requirements for translation initiation and ubiquitination in driving adipogenic fate change is a research paper published in Genes & Development (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (16 grants)OA: goldTopics (44)IDs (PubMed)

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Authors (16)

Keren I. Hilgendorf ORCID,Carl T. Johnson ORCID,Kyuho Han ORCID,Mohammad Ovais Aziz‐Zanjani,Samuel Swails Bollinger

Live enrichment

PubMed:40675820

National Institutes of Health

Grant: 5R01GM114276

National Institutes of Health

Grant: 5U01CA199216

National Institutes of Health

Grant: 5UL1TR00108502

National Institutes of Health

Grant: 1F32GM142180-01A1

The Role of eIF4G1 and eIF4G2 in Translational Control of Adipogenesis and Obesity

National Institutes of Health

Grant: 1K99GM154060-01

TULP3 integrates essential ciliary functions

National Institutes of Health

Grant: 1DP2HD084069-01

Accelerating drug development and repurposing using systematic genetic interactio

National Institutes of Health

Grant: DK125260

National Institutes of Health

Grant: DK111916

National Institutes of Health

Grant: P30DK116074

National Institutes of Health

Grant: TG2-01159

National Institutes of Health

Grant: T32 AG000266

National Institutes of Health

Grant: 5 T32 GM007276

Damon Runyon Cancer Research Foundation

Grant: DRG-2210-14

Walter V. and Idun Berry

Grant: NNF16OC0018642

Novo Nordisk Foundation

Grant: unidentified

unidentified

NIDDK NIH HHS

Grant: R01 DK125260

goldLicense: cc-by-nc

publisherhttps://doi.org/10.1101/gad.352779.125

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.352779.125

repositoryhttps://infoscience.epfl.ch/handle/20.500.14299/254564

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12487700/

https://pubmed.ncbi.nlm.nih.gov/40675820

Fields of Study

0301 basic medicine03 medical and health sciencesAnimalsMiceUbiquitinationAdipogenesis3T3-L1 CellsLipogenesisAdipocytesPeptide Chain Initiation, TranslationalCRISPR-Cas SystemsClustered Regularly Interspaced Short Palindromic RepeatsMitosis

MeSH Terms

AnimalsMiceUbiquitinationAdipogenesis3T3-L1 CellsLipogenesisAdipocytesPeptide Chain Initiation, TranslationalCRISPR-Cas SystemsClustered Regularly Interspaced Short Palindromic RepeatsMitosis

Keywords

AdipogenesisLipogenesisUbiquitinationMitosisMice3T3-L1 CellsAdipocytesAnimalsClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsPeptide Chain Initiation, TranslationalResource/MethodologyCRISPRNedd8hypusinelipidmitotic expansionobesitytranslation initiationubiquitin-dependent proteolysis