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Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503

Genes & Development(2025)10.1101/gad.353138.125Source: DataRank Database

Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503 is a research paper published in Genes & Development (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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Enrichment:Funding (9 grants)OA: goldTopics (30)IDs (PubMed, PMC, OpenAlex)Annotations (2)

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Open Access

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Authors (10)

Jaeil Han ORCID,He Zhang ORCID,Sihoon Cho,Min‐Seon Kim ORCID,Komal Sethia

Live enrichment

PubMed:41213800 PMC:PMC12863257 OpenAlex:https://openalex.org/W4416077822

Cancer Prevention and Research Institute of Texas

Grant: RP220309

Welch Foundation

Grant: I-1961-20240404

National Institutes of Health

Grant: R01CA282036

National Research Foundation of Korea

Grant: RS-2024-00399517

Korean Ministry of Science

Grant: RS-2024-00335939

Korean Ministry of Science

Grant: RS-2025-00556082

NCI NIH HHS

Grant: U01 CA305105

Information and Communication Technology

Brain Pool Program

goldLicense: cc-by

journalhttp://genesdev.cshlp.org/content/early/2025/11/10/gad.353138.125.full.pdf

publisherhttp://genesdev.cshlp.org/content/early/2025/11/10/gad.353138.125.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.353138.125

journalhttps://doi.org/10.1101/gad.353138.125

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41213800

Fields of Study

MicroRNA in disease regulationRNA Research and SplicingMicrotubule and mitosis dynamics

MeSH Terms

AnimalsDNA-Binding ProteinsFibroblastsTranscription FactorsRNA-Binding ProteinsGene Expression Regulation, DevelopmentalRNA StabilityMicroRNAsBody SizeMiceRNA, Long Noncoding

Keywords

microRNAArgonauteEmbryonic stem cellUbiquitinHEK 293 cellsRegulation of gene expressionFunction (biology)RNA-binding proteinRNAMir-503Plagl1Embryonic GrowthMir-322Lrrc58TdmdTarget-directed Microrna Degradation

Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503

FAIR Checklist

Authors (10)

Funding (9 grants)

Open Access

Topics

Annotations (Europe PMC)