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Long-read single-cell RNA sequencing enables the study of cancer subclone-specific genotypes and phenotypes in chronic lymphocytic leukemia

Genome Research(2025)10.1101/gr.279049.124Source: DataRank Database

Long-read single-cell RNA sequencing enables the study of cancer subclone-specific genotypes and phenotypes in chronic lymphocytic leukemia is a research paper published in Genome Research (2025). On theSindex it has a DataRank of 0.331. It has been cited 6 times, with 6 citing works in its 1-hop citation network.

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0.331DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access6 citations · 6 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE259253

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)OA: bronzeTopics (36)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 88%Citation Network 12%

Base Score Contribution

0.292

From this paper's citation signal

Citation Network Contribution

0.0389

From 1 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 6 citers.

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Genome Research20250 citations39 referencesContributes 0.000
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bioRxiv (Cold Spring Harbor Laboratory)20250 citations24 referencesContributes 0.000
Synergistic role of multi-omics analysis combined with multimodal imaging in precision diagnosis and treatment of thoracic and abdominal tumors
Current Radiopharmaceuticals20260 citations86 referencesContributes 0.000
Current trends and challenges in deciphering single molecule resolution maps of single cell transcriptomes
Briefings in Bioinformatics20260 citations54 referencesContributes 0.000

Authors (8)

Xiaomeng Huang ORCID,Yi Qiao ORCID,Philip J. Moos ORCID,Deepa Sampath ORCID,Deborah M. Stephens ORCID

Live enrichment

PubMed:39965935 PMC:PMC12047255 OpenAlex:https://openalex.org/W4407687400

National Cancer Institute of the National Institutes of Health

Grant: P30 CA042014

National Institutes of Health

Grant: 1S10OD021644-01A1

From genomics to natural language processing: A protected environment for research computing in the health science

NCI NIH HHS

Grant: U54 CA224076

National Institutes of Health

Grant: 2U54CA224076-05

PDX Trial Center for Breast Cancer Therapy

OSU Comprehensive Cancer Center Leukemia Tissue

Grant: NCI P30 CA016058

NCI NIH HHS

Grant: P30 CA016058

NIH HHS

Grant: S10 OD021644

NCI NIH HHS

Grant: R50 CA275929

NCI NIH HHS

Grant: U24 CA209999

National Institutes of Health

Grant: 3P30CA016058-15S1

CORE--HORMONE RECEPTOR LABORATORY

National Institutes of Health

Grant: 3U54CA224076-01S2

PDX Trial Center for Breast Cancer Therapy

National Institutes of Health

Grant: 5U24CA209999-05

Monitoring tumor subclonal heterogeneity over time and space

National Institutes of Health

Grant: 3P30CA042014-30S2

Cancer Center Support Grant

National Institutes of Health

Grant: 5R50CA275929-03

Curing Through Collaboration: Utilizing Cooperative Groups in the Fight Against Chronic Lymphocytic Leukemia and B-cell Lymphomas

bronzeLicense: CC BY NC

journalhttps://genome.cshlp.org/content/early/2025/02/18/gr.279049.124.full.pdf

publisherhttps://genome.cshlp.org/content/early/2025/02/18/gr.279049.124.full.pdf

journalhttps://doi.org/10.1101/gr.279049.124

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39965935

repositoryhttps://digitalcommons.library.tmc.edu/uthgsbs_docs/6464

Fields of Study

Chronic Lymphocytic Leukemia ResearchSingle-cell and spatial transcriptomicsCancer Genomics and Diagnostics0206 medical engineering02 engineering and technology

MeSH Terms

Agammaglobulinaemia Tyrosine KinaseGenotypeHumansMutationPhenotypeLeukemia, Lymphocytic, Chronic, B-CellSequence Analysis, RNASingle-Cell AnalysisTranscriptome

Keywords

Bruton's tyrosine kinaseChronic lymphocytic leukemiaBiologyCancer researchMutationGeneCancerGeneticsPhenotypeLeukemiaTyrosine kinaseMolecular biologySignal transductionGenotypeSequence Analysis, RNAResearchAgammaglobulinaemia Tyrosine KinaseHumansSingle-Cell AnalysisTranscriptomeLeukemia, Lymphocytic, Chronic, B-CellArticle

Sustainable Development Goals

SDG 0: Good health and well-being